乙基3-(3-甲基苯基)丙酸酯合成路线 （共 4 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethanol
T=20°C;
参考文献
Taisho Pharmaceutical Co. Ltd.
Patent: EP1650202 A1, 2006 ;
Location in patent: Page/Page column 10-11 ;
反应条件
tributyl-amine; tetrabutyl-ammonium chloride; palladium diacetate in N,N-dimethyl-formamide
T=90°C; 3 h;
参考文献
Battistuzzi, Gianfranco; Cacchi, Sandro; Fabrizi, Giancarlo; Bernini, Roberta
Synlett, 2003 , # 8 p. 1133 - 1136
反应条件
1: HCl / diethyl ether / Heating
2: H2 / PtO2 / ethanol
View Scheme
参考文献
Orr; Musso; Boswell; Kelley; Joyner; Davis; Baccanari
Journal of Medicinal Chemistry, 1995 , vol. 38, # 19 p. 3850 - 3856
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran
T=0 - 20°C; 1.5 h;
2: With water; ammonium chloride in tetrahydrofuran
参考文献
Taisho Pharmaceutical Co. Ltd.
Patent: EP1650202 A1, 2006 ;
Location in patent: Page/Page column 10-11 ;
