alpha,alpha-二甲基-4-亚甲基环己烷甲醇合成路线 （共 14 条）
反应条件
n-butyllithium; potassium tert-butylate in hexane
T=60°C; 48 h;
参考文献
Deagostino; Tivola; Prandi; Venturello
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 21 p. 2856 - 2860
反应条件
1: AcCl / methanol
2: diethyl ether
View Scheme
参考文献
Wilson,S.R. et al.
Journal of the American Chemical Society, 1979 , vol. 101, # 12 p. 3340 - 3344
反应条件
in diethyl ether
0.5 h; Ambient temperature;
参考文献
Hosomi, Akira; Iguchi, Hirokazu; Sasaki, Jun-ichi; Sakurai, Hideki
Tetrahedron Letters, 1982 , vol. 23, # 5 p. 551 - 554
反应条件
1: 64 percent / aluminium chloride / benzene / 3.5 h / 15 - 20 °C / without cat. at 80 deg C, 36 h
2: KF / dimethylsulfoxide / 12 h / 120 °C
3: 93 percent / diethyl ether / 0.5 h / Ambient temperature
View Scheme
参考文献
Hosomi, Akira; Iguchi, Hirokazu; Sasaki, Jun-ichi; Sakurai, Hideki
Tetrahedron Letters, 1982 , vol. 23, # 5 p. 551 - 554
反应条件
1: KF / dimethylsulfoxide / 12 h / 120 °C / Method for preparation of exo-methylenecyclohexanes and cyclohexenes.
2: 2.) HCl / 1.) Et2O, 35 deg C, 2 h, 2.) methanol, r.t., 20 min
View Scheme
参考文献
Sakurai, Hideki; Hosomi, Akira; Saito, Masaki; Sasaki, Koshi; Iguchi, Hirokazu; et al.
Tetrahedron, 1983 , vol. 39, # 6 p. 883 - 894
参考文献
Wilson,S.R. et al.
Journal of the American Chemical Society, 1979 , vol. 101, # 12 p. 3340 - 3344
反应条件
water; mercury dichloride in acetone
Ambient temperatureother mercury(II) salts ( Hg(ClO4)2, Hg(NO3)2, HgSO4); n.m.r. evidence for an intermediate organomercury(II) compound (can be reduced by NaBH4); SE2' mechanism in the conversion of intermediate into product (labelled atoms evidence); MechanismProduct distribution;
参考文献
Bluthe, Norbert; Ecoto, Jules; Fetizon, Marcel; Lazare, Sylvain
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 1747 - 1751
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Bull, Steven D.; Carman, Raymond M.
Australian Journal of Chemistry, 1993 , vol. 46, # 12 p. 1869 - 1880
参考文献
Vig,O.P. et al.
Journal of the Indian Chemical Society, 1967 , vol. 44, # 5 p. 388 - 390
反应条件
N-bromosuccinmide; acetic acid; zinc
1.) acetone, water, 30 min, 2.) ether, 30 min; Multistep reaction;
参考文献
Bull, Steven D.; Carman, Raymond M.
Australian Journal of Chemistry, 1992 , vol. 45, # 12 p. 2077 - 2081
