2-(溴甲基)-6-甲氧基萘合成路线 （共 10 条）
反应条件
1: K2CO3 / acetone / 3 h / Heating 2: 4 g / KOH / H2O / 6 h / Heating View Scheme
参考文献
Srinivasulu; Reddy, A. Raghupathi; Nagaraju; Reddy, P. Pratap; Reddy, M. Satyanarayana
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2005 , vol. 44, # 1 p. 207 - 208
反应条件
tetrabutylammomium bromide in dichloromethane; water T=50°C; 29 h;
参考文献
CORTICAL PTY LTD
Patent: WO2003/104178 A1, 2003 ;
Location in patent: Page 88 ;
反应条件
N-benzyl-N,N,N-triethylammonium chloride in dichloromethane; water 20 h; Heating;
参考文献
McCarthy, James R.; Huffman, John C.
Journal of Organic Chemistry, 1984 , vol. 49, # 25 p. 4995 - 4997
反应条件
phosphorus tribromide in diethyl ether
T=-40 - 20°C; 2 h;
参考文献
Wang, Ji-Quan; Weyand, Eric H; Harvey, Ronald G
The Journal of organic chemistry, 2002 , vol. 67, # 17 p. 6216 - 6219
反应条件
N-bromosuccinmide; azoisobutyric acid dinitrile in tetrachloromethane
参考文献
Beecham Group p.l.c.
Patent: US5068458 A1, 1991 ;
反应条件
1: 96 percent / LiAlH4 / tetrahydrofuran / 8 h / 20 °C
2: PBr3 / tetrahydrofuran / -40 - 20 °C
View Scheme
参考文献
Shi, Zhen-Dan; Yang, Bing-Hui; Zhao, Jing-Jing; Wu, Yu-Lin; Ji, Yong-Yong; Yeh, Ming
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 7 p. 2171 - 2175
反应条件
1: (saponification)
2: HBr
View Scheme
参考文献
Schreiber,K.C.; Byers,R.G.
Journal of the American Chemical Society, 1962 , vol. 84, p. 859 - 862
参考文献
Schreiber,K.C.; Byers,R.G.
Journal of the American Chemical Society, 1962 , vol. 84, p. 859 - 862
反应条件
1: 83 percent / aq. NaClO; NaOH / dioxane / 48 h / 90 °C
2: 96 percent / LiAlH4 / tetrahydrofuran / 8 h / 20 °C
3: PBr3 / tetrahydrofuran / -40 - 20 °C
View Scheme
参考文献
Shi, Zhen-Dan; Yang, Bing-Hui; Zhao, Jing-Jing; Wu, Yu-Lin; Ji, Yong-Yong; Yeh, Ming
Bioorganic and Medicinal Chemistry, 2002 , vol. 10, # 7 p. 2171 - 2175
反应条件
1: 95 percent / LiAlH4
2: 50 percent / PBr3 / benzene / 12 h / Ambient temperature
View Scheme
参考文献
Mukerjee, Y. N.; Gaur, S. P.; Jain, P. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1985 , vol. 24, p. 985 - 987
