4,6-二氯烟酸合成路线

参考文献

Platts, Michelle Y.; Barber, Christopher G.; Chiva, Jean-Yves; Eastwood, Rachel L.; Fenwick, David R.; Paradowski, Kerry A.; Blakemore, David C.
Tetrahedron Letters, 2011 , vol. 52, # 4 p. 512 - 514

73027-79-94,6-二氯烟酸

405230-82-22,5-二氯-4-氨基吡啶

参考文献

den Hertog et al.
Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 673,690

73027-79-94,6-二氯烟酸

40296-46-64,6-二氯烟酸乙酯

参考文献

Kohlmann, Anna; Zech, Stephan G.; Li, Feng; Zhou, Tianjun; Squillace, Rachel M.; Commodore, Lois; Greenfield, Matthew T.; Lu, Xiaohui; Miller, David P.; Huang, Wei-Sheng; Qi, Jiwei; Thomas, R. Mathew; Wang, Yihan; Zhang, Sen; Dodd, Rory; Liu, Shuangying; Xu, Rongsong; Xu, Yongjin; Miret, Juan J.; Rivera, Victor; Clackson, Tim; Shakespeare, William C.; Zhu, Xiaotian; Dalgarno, David C.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 3 p. 1023 - 1040

73027-79-94,6-二氯烟酸

28443-69-84-氨基-2,3,5-三氯吡啶

参考文献

den Hertog et al.
Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 673,690

67-56-1甲醇+

73027-79-94,6-二氯烟酸

716362-10-64-甲氧基-6-氯烟酸

参考文献

BRISTOL-MYERS SQUIBB COMPANY; MOSLIN, Ryan M.; LIN, Shuqun; WEINSTEIN, David S.; WROBLESKI, Stephen T.; ZHANG, Yanlei; TOKARSKI, John S.
Patent: WO2014/74660 A1, 2014 ;
Location in patent: Paragraph 00163 ;

73027-79-94,6-二氯烟酸

70593-57-64,6-二氯吡啶-3-酰胺

参考文献

Boehringer Ingelheim International GmbH
Patent: US2006/217417 A1, 2006 ;
Location in patent: Page/Page column 12; 13 ;

73027-79-94,6-二氯烟酸+

2592-95-21-羟基苯并三唑

参考文献

Portola Pharmaceuticals, Inc.
Patent: US2012/108566 A1, 2012 ;
Location in patent: Page/Page column 55 ;
US 20120108566 A1

73027-79-94,6-二氯烟酸

7321-93-92,4-二氯-5-氨基吡啶

参考文献

den Hertog et al.
Recueil des Travaux Chimiques des Pays-Bas, 1950 , vol. 69, p. 673,690

73027-79-94,6-二氯烟酸

166526-03-04,6-二氯烟腈

参考文献

Recueil des Travaux Chimiques des Pays-Bas, , vol. 69, p. 673,690

109-83-1N-甲基-2-羟基乙胺+

73027-79-94,6-二氯烟酸

919788-64-0

参考文献

ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/7040 A1, 2007 ;
Location in patent: Page/Page column 50; 61 ;
WO 2007/007040 A1