甲基1-乙基-1H-吡咯-2-羧酸酯合成路线 (共 1 条)
反应条件
1: methyl ester of pyrrole-2-carboxylic acid With 18-crown-6 ether; potassium tert-butylate in diethyl ether
T=0°C;
2: ethyl iodide in diethyl ether
T=20°C; 17 h;
参考文献
Mizuno; Miya; Kamei; Shibata; Tatsuoka; Nakanishi; Takiguchi; Hidaka; Yamaki; Inomata
Chemical and Pharmaceutical Bulletin, 2000 , vol. 48, # 8 p. 1129 - 1137