1-(吡咯烷-1-基甲基)吡咯烷合成路线 （共 20 条）
反应条件
1: 70 percent / conc. hydrochloric acid / CHCl3
2: conc. hydrochloric acid, sodium nitrite / H2O / -6 °C
3: 70 percent / LiAlH4 / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Miquel, Christian; Pigache, Pierre; Rigo, Benoit; Kolocouris, Nicolas
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1447 - 1453
反应条件
1: 81 percent / hydrazine hydrate / ethanol / 10 h / Heating
2: conc. hydrochloric acid, sodium nitrite / H2O; CHCl3 / -5 °C
3: CHCl3 / 50 °C
4: 70 percent / conc. hydrochloric acid / CHCl3
5: conc. hydrochloric acid, sodium nitrite / H2O / -6 °C
6: 70 percent / LiAlH4 / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Miquel, Christian; Pigache, Pierre; Rigo, Benoit; Kolocouris, Nicolas
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1447 - 1453
反应条件
1: CHCl3 / 50 °C
2: 70 percent / conc. hydrochloric acid / CHCl3
3: conc. hydrochloric acid, sodium nitrite / H2O / -6 °C
4: 70 percent / LiAlH4 / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Miquel, Christian; Pigache, Pierre; Rigo, Benoit; Kolocouris, Nicolas
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1447 - 1453
反应条件
1: conc. hydrochloric acid, sodium nitrite / H2O / -6 °C
2: 70 percent / LiAlH4 / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Miquel, Christian; Pigache, Pierre; Rigo, Benoit; Kolocouris, Nicolas
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1447 - 1453
反应条件
1: conc. hydrochloric acid, sodium nitrite / H2O; CHCl3 / -5 °C
2: CHCl3 / 50 °C
3: 70 percent / conc. hydrochloric acid / CHCl3
4: conc. hydrochloric acid, sodium nitrite / H2O / -6 °C
5: 70 percent / LiAlH4 / tetrahydrofuran / 24 h / Heating
View Scheme
参考文献
Miquel, Christian; Pigache, Pierre; Rigo, Benoit; Kolocouris, Nicolas
Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1447 - 1453
反应条件
in methanol
P=6750540 Torr; 48 h; Ambient temperature;
参考文献
Matsumoto, Kiyoshi; Hashimoto, Shiro; Ikemi, Yukio; Otani, Shinichi
Heterocycles, 1984 , vol. 22, # 6 p. 1417 - 1420
反应条件
in methanol
20 h; Heating; Yield given;
参考文献
Tacke, Reinhold; Sperlich, Joerg; Becker, Beate
Chemische Berichte, 1994 , vol. 127, # 4 p. 643 - 646
反应条件
acetyl chloride in diethyl ether
参考文献
Mills, John E.; Maryanoff, Cynthia A.; McComsey, David F.; Stanzione, Robin C.; Scott, Lorraine
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1857 - 1859
参考文献
Moehrle, Hans; Arz, Petra
Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1987 , vol. 42, # 8 p. 1035 - 1046
反应条件
1: acetyl chloride / diethyl ether
2: 66 percent / acetonitrile / 120 h / Ambient temperature
View Scheme
参考文献
Heaney, Harry; Papageorgiou, George; Wilkins, Robert F.
Tetrahedron Letters, 1988 , vol. 29, # 19 p. 2377 - 2380
