7-氯-2-(氯甲基)-4(3h)-喹唑啉酮合成路线 (共 2 条)
反应条件
potassium carbonate in water; acetone
T=70°C; 1.5 h; Microwave irradiation;
参考文献
Kabri, Youssef; Verhaeghe, Pierre; Gellis, Armand; Vanelle, Patrice
Molecules, 2010 , vol. 15, # 5 p. 2949 - 2961
反应条件
1: chloroacetonitrile With sodium in methanol
T=25°C; 0.666667 h; Inert atmosphere;
2: 4-chloro-2-amino-benzoic acid in methanol
T=25°C; 4 h; Inert atmosphere;
参考文献
Li, Hong-Ze; He, Hai-Yun; Han, Yuan-Yuan; Gu, Xin; He, Lin; Qi, Qing-Rong; Zhao, Ying-Lan; Yang, Li
Molecules, 2010 , vol. 15, # 12 p. 9473 - 9485