6-甲基-3-苯基-2-喹啉醇合成路线 （共 11 条）
反应条件
trichlorophosphate in water; acetic acid; ethyl acetate; N,N-dimethyl-formamide
参考文献
Laboratoire L. Lafon
Patent: US6593342 B1, 2003 ;
反应条件
aluminium trichloride in chlorobenzene
T=95°C; 3 h;
参考文献
Natarajan, M.; Ramakrishnan, V. T.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 8 p. 720 - 727
反应条件
aluminium trichloride in chlorobenzene
T=95°C; 4 h;
参考文献
Natarajan, M.; Ramakrishnan, V. T.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 8 p. 720 - 727
反应条件
aluminium trichloride in chlorobenzene
T=95°C;
参考文献
Natarajan, M.; Manimaran, T.; Ramakrishnan, V. T.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 6 p. 529 - 534
反应条件
1: acetophenone; 1-(4-methylphenyl)hydrazine With phosphoric acid in water
T=100 - 110°C; 0.666667 h;
2: β-NO2 styrene With water
T=80 - 85°C; 0.5 h; Further stages;
参考文献
Aksenov, Alexander V.; Smirnov, Alexander N.; Aksenov, Nicolai A.; Aksenova, Inna V.; Frolova, Liliya V.; Kornienko, Alexander; Magedov, Igor V.; Rubin, Michael
Chemical Communications, 2013 , vol. 49, # 81 p. 9305 - 9307
反应条件
palladium diacetate; triethylamine; 1,2-bis-(diphenylphosphino)ethane in tetrahydrofuran
T=60 - 160°C; 0.666667 h; Inert atmosphereMicrowave irradiation;
参考文献
Chen, Jia-Rong; Liao, Jie; Xiao, Wen-Jing
Canadian Journal of Chemistry, 2010 , vol. 88, # 4 p. 331 - 337
反应条件
aluminium trichloride
T=95°C; 5 h;
参考文献
Eicher, Theophil; Schneider, Volker
Synthesis, 1989 , # 5 p. 372 - 378
反应条件
in 1,2,3,4-tetrahydro-naphthalene
T=150°C; 6 h;
参考文献
Eicher, Theophil; Schneider, Volker
Synthesis, 1989 , # 5 p. 372 - 378
反应条件
1: 1.) AlCl3 / 1.) CH2Cl2, 0 deg C, 2 h, 2.) 20 deg C, 2 h; 80 deg C, 2 h
2: 39 percent / 1,2,3,4-tetrahydro-naphthalene / 6 h / 150 °C
View Scheme
参考文献
Eicher, Theophil; Schneider, Volker
Synthesis, 1989 , # 5 p. 372 - 378
反应条件
1: 1.) AlCl3 / 1.) CH2Cl2, 0 deg C, 2 h, 2.) 20 deg C, 2 h; 80 deg C, 2 h
2: 39 percent / 1,2,3,4-tetrahydro-naphthalene / 6 h / 150 °C
View Scheme
参考文献
Eicher, Theophil; Schneider, Volker
Synthesis, 1989 , # 5 p. 372 - 378
