3,5-二甲氧基苯甲醛合成路线 （共 226 条）
反应条件
iodine; mercury(II) oxide in benzene
参考文献
Harrowven, David C.; Nunn, Michael I.T.; Fenwick, David R.
Tetrahedron Letters, 2002 , vol. 43, # 41 p. 7345 - 7347
反应条件
1: 82 percent / benzene / 288 h / 20 °C
2: 63 percent / potassium acetate / 0.25 h / Heating
3: 93 percent / potassium carbonate; methanol / acetone / 3 h / 35 °C
4: potassium carbonate / acetone / 16 h / Heating
View Scheme
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
1.) Stobbe reaction; 2.) cyclisation and methylation; Multistep reaction;
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.
Tetrahedron Letters, 1980 , vol. 21, p. 1385 - 1386
反应条件
1: sodium tetrahydroborate / methanol / 0.17 h / 20 °C
2: N-bromosuccinmide / tetrahydrofuran / 20 °C
View Scheme
参考文献
De, Subhadip; Chaudhuri, Saikat; Mishra, Sourabh; Mamtani, Himanshu; Bisai, Alakesh
Journal of the Indian Chemical Society, 2013 , vol. 90, # 10 p. 1871 - 1884
反应条件
1: 82 percent / benzene / 288 h / 20 °C
2: 63 percent / potassium acetate / 0.25 h / Heating
View Scheme
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.
Australian Journal of Chemistry, 1980 , vol. 33, # 11 p. 2531 - 2541
反应条件
1: 70 percent / potassium / 2-methyl-propan-2-ol / 0.5 h / Heating
2: 46 percent / sodium acetate / 6 h / Heating
3: 96 percent / aq. NaOH / 1 h / Heating
View Scheme
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.
Australian Journal of Chemistry, 1980 , vol. 33, # 11 p. 2531 - 2541
反应条件
1: 74 percent / propionic anhydride / 15 h / 155 - 160 °C
2: 100 percent / H2 / 10percent Pd/C / ethyl acetate / 20 h / 1551.4 Torr
3: 88 percent / polyphosphoric acid (PPA) / 0.2 h / 90 °C
4: 88 percent / 1.5 h / Ambient temperature
5: 61 percent / O3 / ethyl acetate / 15 h / -55 °C
6: H2 / 10percent Pd/C
View Scheme
参考文献
Kendall, J. Kirby; Fisher, Thomas H.; Schultz, Harry P.; Schultz, Tor P.
Journal of Organic Chemistry, 1989 , vol. 54, # 17 p. 4218 - 4220
反应条件
potassium tert-butylate
参考文献
Cameron, Donald W.; Feutrill, Geoffrey I.; Pannan, Linda J. H.; Raston, Colin L.; Skelton, Brian W.; White, Allan H.
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1981 , p. 610 - 627
反应条件
1: 82 percent / benzene / 288 h / 20 °C
2: 63 percent / potassium acetate / 0.25 h / Heating
3: 93 percent / potassium carbonate; methanol / acetone / 3 h / 35 °C
View Scheme
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
1: N-bromosuccinmide / acetonitrile / |Cooling with ice
2: sodium hydroxide; copper; water / 24 h / |Reflux
View Scheme
参考文献
Yuan, Changxia; Liang, Yong; Hernandez, Taylor; Berriochoa, Adrian; Houk, Kendall N.; Siegel, Dionicio
Nature, 2013 , vol. 499, # 7457 p. 192 - 196
