3,5-二甲氧基苯甲醛合成路线 （共 226 条）
参考文献
Bouvier,P. et al.
European Journal of Medicinal Chemistry, 1976 , vol. 11, p. 271 - 278
反应条件
1: With piperidinium acetate in ethanol
0.5 h;
2: With sodium cyanoborohydride in ethanol
T=0 - 20°C;
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
1: lithium hexamethyldisilazane / tetrahydrofuran / 20 h / 0 °C
2: hydrogenchloride / tetrahydrofuran; water / |Reflux
View Scheme
参考文献
Gualandi, Andrea; Canestrari, Pietro; Emer, Enrico; Cozzi, Pier Giorgio
Advanced Synthesis and Catalysis, 2014 , vol. 356, # 2-3 p. 528 - 536
反应条件
1: triethylamine / 6 h / 110 °C
2: quinoline; copper / 3 h / 200 °C / Inert atmosphere
View Scheme
参考文献
Xiao, Chun-Fen; Zou, Yong; Du, Jian-Li; Sun, Hong-Yi; Liu, Xian-Ke
Synthetic Communications, 2012 , vol. 42, # 9 p. 1243 - 1258
反应条件
1: acetic anhydride; triethylamine
2: copper; quinoline
3: iodine; methyloxirane / cyclohexane / 72 h / |UV-irradiation
View Scheme
参考文献
Ding, De-Jun; Cao, Xiao-Yan; Dai, Fang; Li, Xiu-Zhuang; Liu, Guo-Yun; Lin, Dong; Fu, Xing; Jin, Xiao-Ling; Zhou, Bo
Food Chemistry, 2012 , vol. 135, # 3 p. 1011 - 1019
反应条件
1: sodium tetrahydroborate / methanol
2: tetrachloromethane; triphenylphosphine
View Scheme
参考文献
Jo, Geunhyeong; Hyun, Jiye; Hwang, Doseok; Lee, Young Han; Koh, Dongsoo; Lim, Yoongho
Magnetic Resonance in Chemistry, 2011 , vol. 49, # 6 p. 374 - 377
反应条件
1: 86 percent / tetrahydrofuran / 4 h / -60 °C
2: 79.6 percent / CrO3, aq. H2SO4 / acetone / 0.5 h / Ambient temperature
View Scheme
参考文献
Papahatjis; Kourouli; Abadji; Goutopoulos; Makriyannis
Journal of Medicinal Chemistry, 1998 , vol. 41, # 7 p. 1195 - 1200
反应条件
1: Methyltriphenylphosphonium bromide With potassium tert-butylate in tetrahydrofuran
T=20°C; 0.5 h; Inert atmosphere;
2: 3,5-dimethoxy-benzaldehyde in tetrahydrofuran
T=-78 - 20°C; Inert atmosphere;
参考文献
Smith, Laura H. S.; Nguyen, Trung Thanh; Sneddon, Helen F.; Procter, David J.
Chemical Communications, 2011 , vol. 47, # 38 p. 10821 - 10823
反应条件
1: triphenyl-methyl-phosphonium iodide With potassium tert-butylate in diethyl ether
T=20°C; Wittig reaction; 2 h;
2: 3,5-dimethoxy-benzaldehyde in diethyl ether
T=0 - 20°C; Wittig reaction;
参考文献
Jana, Nandan; Nanda, Samik
European Journal of Organic Chemistry, 2012 , # 23 p. 4313 - 4320
反应条件
Methyltriphenylphosphonium bromide; sodium hydride in tetrahydrofuran; mineral oil
T=20°C; Inert atmosphere;
参考文献
Schmidt, Bernd; Elizarov, Nelli; Berger, Rene; Hoelter, Frank
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 22 p. 3674 - 3691
