3,5-二甲氧基苯甲醛合成路线 （共 226 条）
反应条件
1.1: 93 percent / NaBH4 / methanol / 0 °C 2.1: 89 percent / PBr3 / CH2Cl2 / 12 h / 0 °C 3.1: 92 percent / toluene / 12 h / Heating 4.1: n-BuLi / tetrahydrofuran / -78 °C 4.2: tetrahydrofuran 5.1: 90 percent / Bu4NF / tetrahydrofuran View Scheme
参考文献
Schmidt, Bernd; Elizarov, Nelli; Berger, Rene; Hoelter, Frank
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 22 p. 3674 - 3691
反应条件
1: sodium tetrahydroborate / methanol 2: tetrachloromethane; triphenylphosphine 4: Alkaline conditions View Scheme
参考文献
Jo, Geunhyeong; Hyun, Jiye; Hwang, Doseok; Lee, Young Han; Koh, Dongsoo; Lim, Yoongho
Magnetic Resonance in Chemistry, 2011 , vol. 49, # 6 p. 374 - 377
反应条件
1: acetic anhydride; triethylamine / 6 h / 110 °C 2: quinoline; copper / 3 h / 200 °C / Inert atmosphere View Scheme
参考文献
Xiao, Chun-Fen; Zou, Yong; Du, Jian-Li; Sun, Hong-Yi; Liu, Xian-Ke
Synthetic Communications, 2012 , vol. 42, # 9 p. 1243 - 1258
反应条件
1: nitric acid / -5 °C 2: aqueous KOH View Scheme
参考文献
Lock; Nottes
Monatshefte fuer Chemie, 1936 , vol. 68, p. 51,60
反应条件
1: 1.) Mg; MeI / diethyl ether / 1.) 3 h, reflux; 2.) 1 h, reflux 2: hydrogen, conc. H2SO4 / 10percent Pd-C / ethyl acetate / 4 h / 2942.03 Torr / Ambient temperature 3: NaI, ClSiMe3 / acetonitrile / 36 h / Heating View Scheme
参考文献
Ayer, William A.; Browne, Lois M.; Lovell, Sarah H.
Phytochemistry (Elsevier), 1983 , vol. 22, # 10 p. 2267 - 2272
反应条件
potassium cyanide; tetra-(n-butyl)ammonium iodide in N,N-dimethyl-formamide 18 h; Inert atmosphere;
参考文献
Arifin, Khuzaimah; Minggu, Lorna Jeffery; Daud, Wan Ramli Wan; Yamin, Bohari M.; Daik, Rusli; Kassim, Mohammad B.
Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, 2014 , vol. 120, p. 208 - 215
反应条件
benzaldehyde lyase from Pseudomonas fluorescens; thiamine diphosphate; magnesium chloride in dimethyl sulfoxide T=20°C; pH=7.0; 24 h; aq. phosphate bufferInert atmosphereEnzymatic reaction; optical yield given as percent ee;
参考文献
Cosp, Anabel; Dresen, Carola; Pohl, Martina; Walter, Lydia; Roehr, Caroline; Mueller, Michael
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 5 p. 759 - 771
反应条件
benzaldehyde lyase from Pseudomonas fluorescens; thiamine diphosphate; magnesium chloride pH=7.0; aq. phosphate bufferEnzymatic reaction;
参考文献
Cosp, Anabel; Dresen, Carola; Pohl, Martina; Walter, Lydia; Roehr, Caroline; Mueller, Michael
Advanced Synthesis and Catalysis, 2008 , vol. 350, # 5 p. 759 - 771
参考文献
Corrie, John E. T.; Trentham, David R.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 18 p. 2409 - 2418
反应条件
in diethyl ether 2 h; Ambient temperature;
参考文献
Cristol, Stanley J.; Ali, Mahfuza B.; Sankar, Iyer V.
Journal of the American Chemical Society, 1989 , vol. 111, # 21 p. 8207 - 8211
