3,5-二甲氧基苯甲醛合成路线 （共 226 条）
反应条件
1: 62 percent / NH4OAc / 16 h / 100 °C 2: 90 percent / Fe, glacial AcOH / 3 h / Heating View Scheme
参考文献
Hoye, Thomas R.; Chen, Minzhang; Mi, Liang; Priest, Owen P.
Tetrahedron Letters, 1994 , vol. 35, # 47 p. 8747 - 8750
反应条件
ammonium acetate T=100°C; 16 h;
参考文献
Upender; Pollart; Liu; Hobbs; Olsen; Chao; Bowden; Crase; Thomas; Pandey; Lawson; Dawson
Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 4 p. 1371 - 1385
反应条件
1: LiN(iPr)2, acid / tetrahydrofuran; H2O / -78 °C / to RT 2: pyridinium p-toluenesulfonate / toluene / Heating View Scheme
参考文献
Lu, Chuanjun; Guo, Yueyan; Li, Jianheng; Yao, Meicun; Liao, Qiongfeng; Xie, Zhiyong; Li, Xingshu
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 24 p. 7683 - 7687
反应条件
1: 36 percent / potassium tert-butoxide / benzene / 1.) room temp., 20 h, 2.) 60 deg C, 1 h 2: H2 / 10percent Pd/C / ethanol View Scheme
参考文献
Eiden; Gerstlauer
Archiv der Pharmazie, 1981 , vol. 314, # 12 p. 995 - 1006
反应条件
triphenylphosphine in dichloromethane T=0 - 20°C; 0.5 h;
参考文献
Xia, Yan; Jin, Yinglan; Kaur, Navneet; Choi, Yongseok; Lee, Kyeong
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 6 p. 2386 - 2396
反应条件
1: 82 percent / benzene / 288 h / 20 °C 2: 63 percent / potassium acetate / 0.25 h / Heating 3: 93 percent / potassium carbonate; methanol / acetone / 3 h / 35 °C 4: potassium carbonate / acetone / 16 h / Heating 5: LiAlH4 / tetrahydrofuran / 1 h / 20 °C View Scheme
参考文献
Piettre, Arnaud; Chevenier, Emmanuel; Massardier, Christine; Gimbert, Yves; Greene, Andrew E.
Organic Letters, 2002 , vol. 4, # 18 p. 3139 - 3142
反应条件
1: 57 percent / NaOCH3 / methanol / 7 h / Heating 2: 10.2 percent / NaOCH3 / 48 h / Heating View Scheme
参考文献
EGIS Gyogyszergyar
Patent: US4883798 A1, 1989 ;
反应条件
1: 93 percent / NaBH4 / methanol / 0 °C 2: 89 percent / PBr3 / CH2Cl2 / 12 h / 0 °C 3: 92 percent / toluene / 12 h / Heating View Scheme
参考文献
Parihar, Swati; Kumar, Amit; Chaturvedi, Amit K.; Sachan, Naresh Kumar; Luqman, Suaib; Changkija, Bendangla; Manohar, Murli; Prakash, Om; Chanda; Khan, Feroz; Chanotiya; Shanker, Karuna; Dwivedi, Anila; Konwar, Rituraj; Negi, Arvind S.
Journal of Steroid Biochemistry and Molecular Biology, 2013 , vol. 137, p. 332 - 344
反应条件
1.1: 89 percent / bromine / acetic acid; H2O / 20 °C 2.1: sec-BuLi; TMEDA / tetrahydrofuran / 0.75 h / -78 °C 2.2: 40 percent / tert-BuLi / tetrahydrofuran; pentane / -78 - 20 °C View Scheme
参考文献
Tan, Jason Samuel; Ciufolini, Marco A.
Organic Letters, 2006 , vol. 8, # 21 p. 4771 - 4774
反应条件
3-(1-piperazino)propyl functionalised silica gel in acetonitrile Knoevenagel condensation;
参考文献
Wiles, Charlotte; Watts, Paul; Haswell, Stephen J.
Chemical Communications, 2007 , # 9 p. 966 - 968
