5-乙烯基苯并[1,3]二氧杂环戊烯合成路线 （共 27 条）
反应条件
(SPY-5-31)-dichloro-(κ2(C,O)-(2-isopropyloxybenzylidene))(1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidene)ruthenium; [(t-Bu3P)PdBr]2 in tetrahydrofuran
T=60°C; P=7500.75 Torr; 16 h; Autoclave;
参考文献
Baader, Sabrina; Ohlmann, Dominik M.; Goossen, Lukas J.
Chemistry - A European Journal, 2013 , vol. 19, # 30 p. 9807 - 9810
反应条件
titanium tetrachloride; magnesium in tetrahydrofuran
T=0 - 20°C; 0.833333 h;
参考文献
Yan, Tu-Hsin; Tsai, Chia-Chung; Chien, Ching-Ting; Cho, Chia-Ching; Huang, Pei-Chen
Organic Letters, 2004 , vol. 6, # 26 p. 4961 - 4963
反应条件
potassium tert-butylate; Methyltriphenylphosphonium bromide in tetrahydrofuran
T=0 - 20°C; 1.58333 h;
参考文献
Mercadante, Michael A.; Kelly, Christopher B.; Lee, Christopher; Leadbeater, Nicholas E.
Organic Process Research and Development, 2012 , vol. 16, # 5 p. 1064 - 1068
反应条件
potassium carbonate in tetrahydrofuran
参考文献
University of Rochester
Patent: US4294763 A1, 1981 ;
反应条件
NiCl2((PPh3)P)2 in diethyl ether; benzene
16 h; Heating;
参考文献
Ni, Zhi-Jie; Mei, Nai-Wen; Shi, Xian; Tzeng, Yih-Ling; Wang, Maw Cherng; Luh, Tien-Yau
Journal of Organic Chemistry, 1991 , vol. 56, # 12 p. 4035 - 4042
反应条件
pyridine; acetic acid
T=130°C; Knoevenagel-Doebner reaction; 0.133333 h; microwave irradiation;
参考文献
Sinha, Arun K.; Sharma, Anuj; Joshi, Bhupendra P.
Tetrahedron, 2007 , vol. 63, # 4 p. 960 - 965
反应条件
potassium carbonate in diethylene glycol dimethyl ether
24 h; Heating;
参考文献
Brown, Eric; Dujardin, Gilles; Maudet, Mickael
Tetrahedron, 1997 , vol. 53, # 28 p. 9679 - 9694
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene; copper dichloride / 0.5 h / 240 °C
2: potassium carbonate / N,N-dimethyl-formamide / 4 h / |Reflux
View Scheme
参考文献
El-Behairy, Mohammed Farrag; Sundby, Eirik
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 285 - 289
反应条件
diethyl ether
T=-2°C;
参考文献
Klages; Eppelsheim
Chemische Berichte, 1903 , vol. 36, p. 3595
反应条件
n-butyllithium; (iodomethyl)tri-n-butylstannane
Yield given. Multistep reaction;
参考文献
Ochiai, Masahito; Tada, Shin-ichi; Sumi, Kenzo; Fujita, Eiichi
Tetrahedron Letters, 1982 , vol. 23, # 21 p. 2205 - 2208
