联硼酸频那醇酯合成路线

参考文献

Xiao, Dong; Palani, Anandan; Sofolarides, Michael; Huang, Ying; Aslanian, Robert; Vaccaro, Henry; Hong, Liwu; McKittrick, Brian; West Jr., Robert E.; Williams, Shirley M.; Wu, Ren-Long; Hwa, Joyce; Sondey, Christopher; Lachowicz, Jean
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 2 p. 861 - 864

864774-67-45-溴-3-乙基-1H-吲唑+

73183-34-3联硼酸频那醇酯

864774-69-63-乙基-5-(4,4,5,5-四甲基 -[1,3,2]二氧硼戊环-2-基)-1h-吲唑

参考文献

SMITHKLINE BEECHAM CORPORATION
Patent: WO2005/85227 A1, 2005 ;
Location in patent: Page/Page column 52; 131 ;
WO 2005/085227 A1

866546-10-33-溴-5-氯-1-[(4-甲基苯基)磺酰基]-1H-吡咯并[2,3-b]吡啶+

73183-34-3联硼酸频那醇酯

866546-11-45-氯-3-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1-甲苯磺酰-1H-吡咯并[2,3-b]吡啶

参考文献

VERTEX PHARMACEUTICALS INCORPORATED?
Patent: WO2005/95400 A1, 2005 ;
Location in patent: Page/Page column 345; 348 ;
WO 2005/095400 A1

27007-53-02-溴-5-氯苯甲酸甲酯+

73183-34-3联硼酸频那醇酯

866625-02-7

参考文献

Smallheer, Joanne M.; Corte, James R.
Patent: US2005/228000 A1, 2005 ;
Location in patent: Page/Page column 29 ;
US 20050228000 A1

867006-25-5+

73183-34-3联硼酸频那醇酯

867006-28-82-甲氧基-3-乙基-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)吡啶

参考文献

AVENTIS PHARMACEUTICALS INC.
Patent: WO2005/97750 A1, 2005 ;
Location in patent: Page/Page column 59 ;
WO 2005/097750 A1

867164-56-5+

73183-34-3联硼酸频那醇酯

867164-54-32-苯基-7-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)喹啉

参考文献

OSI PHARMACEUTICALS, INC.
Patent: WO2005/97800 A1, 2005 ;
Location in patent: Page/Page column 410 ;
WO 2005/097800 A1

61687-26-17-氯-2-苯基喹啉+

73183-34-3联硼酸频那醇酯

867164-54-32-苯基-7-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)喹啉

参考文献

OSI PHARMACEUTICALS, INC.
Patent: WO2005/97800 A1, 2005 ;
Location in patent: Page/Page column 413 ;
WO 2005/097800 A1

66584-32-5+

73183-34-3联硼酸频那醇酯

869090-08-4

参考文献

GALDERMA RESEARCH and DEVELOPMENT, S.N.C.
Patent: WO2006/18326 A1, 2006 ;
Location in patent: Page/Page column 27 ;
WO 2006/018326 A1

1520-21-4+

73183-34-3联硼酸频那醇酯

870004-04-9

参考文献

Qiu, Di; Jin, Liang; Zheng, Zhitong; Meng, He; Mo, Fanyang; Wang, Xi; Zhang, Yan; Wang, Jianbo
Journal of Organic Chemistry, 2013 , vol. 78, # 5 p. 1923 - 1933

105942-08-3+

73183-34-3联硼酸频那醇酯

870238-67-8

参考文献

GLAXOSMITHKLINE LLC; AXTEN, Jeffrey, Michael; BLACKLEDGE, Charles, William; BRADY, Gerald, Patrick; FENG, Yanhoug, G.; GRANT, Seth, W.; MEDINA, Jesus, Rahul; MILLER, William, H.; ROMERIL, Stuart, P.
Patent: WO2010/59658 A1, 2010 ;
Location in patent: Page/Page column 149 ;
WO 2010/059658 A1