反应条件
1: 1H-indazol-4-amine With hydrogenchloride; sodium nitrite in water T=0°C; 2: With sodium tetrafluoroborate in water 3: 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl-4',4',5',5'-tetramethyl-1,3,2-dioxaborolane With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in methanol Suzuki Coupling; 5 h; Inert atmosphere;
参考文献
GENENTECH, INC.; F. HOFFMANN-LA ROCHE AG
Patent: WO2009/146406 A1, 2009 ;
Location in patent: Page/Page column 65 ;
WO 2009/146406 A1