potassium hydroxide; tetrakis(triphenylphosphine) palladium(0) in methanol Suzuki coupling; 10 h; Heating;

1: 2-(N-triphenylmethyl-tetrazol-5-yl)-phenylboronic acid With palladium diacetate; triphenylphosphine in tetrahydrofuran; ethylene glycol dimethyl ether T=20°C; 0.666667 h; 2: 3-[4-bromobenzyl]-2-n-butyl-1,3-diazaspiro[4.4]non-1-en-4-one With water; potassium carbonate in tetrahydrofuran; ethylene glycol dimethyl ether T=20 - 80°C; 3.5 h; Heating / reflux;

potassium carbonate; palladium diacetate; triphenylphosphine in water; toluene T=95 - 100°C; 3 - 4 h; Product distribution / selectivity;