4-甲氧基-4-连苯基羧酸乙酯合成路线 （共 49 条）
反应条件
manganese; cobalt (II) bromide; triphenylphosphine; trifluoroacetic acid in pyridine; N,N-dimethyl-formamide T=50°C;
参考文献
Angewandte Chemie - International Edition, , vol. 47, # 11 p. 2089 - 2092
反应条件
[bdmim][BF4]; 1-butyl-2-(diphenylphosphanyl)-3-methylimidazolium hexafluorophosphate; bis(dibenzylideneacetone)-palladium(0) in toluene T=20°C; Substitution; Negishi cross-coupling reaction; 0.3 h;
参考文献
Sirieix; Ossberger; Betzemeier; Knochel
Synlett, 2000 , # 11 p. 1613 - 1615
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Jadhav, Deepak N.
Tetrahedron Letters, 2007 , vol. 48, # 15 p. 2707 - 2711
反应条件
1: 1-bromo-4-methoxy-benzene With diisobutyl-aluminum chloride; diisobutylaluminium hydride; magnesium; lithium chloride in tetrahydrofuran; n-heptane T=25°C; 3 h; 2: 4-bromo-benzoic acid ethyl ester With PEPPSITM-IPr in tetrahydrofuran T=25°C; 4 h;
参考文献
Gao, Hongjun; Knochel, Paul
Synlett, 2009 , # 8 p. 1321 - 1325
反应条件
oxygen; lithium chloride; manganese (II) chloride in tetrahydrofuran T=-5 - 0°C; Inert atmosphere; chemoselective reaction;
参考文献
Angewandte Chemie, International Edition, , vol. 48, # 36 p. 6731 - 6734
反应条件
tetrabutyl ammonium fluoride; palladium dichloride; tri-cyclo-hexyl-phosphine in water; dimethyl sulfoxide T=80°C; 1 h;
参考文献
Nakao, Yoshiaki; Oda, Takuro; Sahoo, K. Akhila; Hiyama, Tamejiro
Journal of Organometallic Chemistry, 2003 , vol. 687, # 2 p. 570 - 573
反应条件
tetrabutyl ammonium fluoride; bis(dibenzylideneacetone)-palladium(0); 2-dicyclohexylphosphino-1,1'-biphenyl in tetrahydrofuran T=120°C; 0.166667 h; microwave irradiation;
参考文献
Seganish, W. Michael; DeShong, Philip
Organic Letters, 2004 , vol. 6, # 23 p. 4379 - 4381
反应条件
1: 1-chloro-1-(4'-methoxyphenyl)silacyclobutane With tetrabutyl ammonium fluoride in tetrahydrofuran 2: 4-iodobenzoic acid ethyl ester With tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; bis(η3-allyl-μ-chloropalladium(II)) in tetrahydrofuran 1 h; Heating; Further stages.;
参考文献
Denmark, Scott E.; Wu, Zhicai
Organic Letters, 1999 , vol. 1, # 9 p. 1495 - 1498
反应条件
potassium carbonate; triphenylphosphine in methanol T=50°C; Suzuki-Miyaura coupling; 24 h;
参考文献
Masuyama, Yoshiro; Sugioka, Yutaka; Chonan, Shiori; Suzuki, Noriyuki; Fujita, Masahiro; Hara, Kenji; Fukuoka, Atsushi
Journal of Molecular Catalysis A: Chemical, 2012 , vol. 352, p. 81 - 85
反应条件
tetrabutyl ammonium fluoride; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in tetrahydrofuran; tert-butyl alcohol T=90°C; Hiyama coupling; Inert atmosphere;
参考文献
Zhang, Liang; Qing, Jiang; Yang, Pengyuan; Wu, Jie
Organic Letters, 2008 , vol. 10, # 21 p. 4971 - 4974
