4-甲氧基-4-连苯基羧酸乙酯合成路线 （共 49 条）
反应条件
palladium diacetate in 1,4-dioxane T=20°C; 56 h;
参考文献
Darses, Sylvain; Jeffery, Tuyet; Genet, Jean-Pierre; Brayer, Jean-Louis; Demoute, Jean-Pierre
Tetrahedron Letters, 1996 , vol. 37, # 22 p. 3857 - 3860
反应条件
1: With [resin-CH2N(CH3)3]2CO3 in water; N,N-dimethyl-formamide T=80°C; Suzuki coupling; 16 h; 2: With [resin-CH2N(CH3)3]2CO3; 4-{[(9-anthrylmethyl)amino]carbonyl}phenylboronic acid in water; N,N-dimethyl-formamide T=80°C; 3: With maleimido-CH2-PS resin in water; N,N-dimethyl-formamide T=90°C; 10 h;
参考文献
Lan, Ping; Berta, Daniela; Porco Jr., John A.; South, Michael S.; Parlow, John J.
Journal of Organic Chemistry, 2003 , vol. 68, # 25 p. 9678 - 9686
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran 2: With zinc dibromide in tetrahydrofuran 3: p-EtOC(O)C6H4Cl With 4-(N,N-dimethlyamino)pyridine; phosphonic acid diethyl ester; nickel dichloride in tetrahydrofuran T=25°C; Negishi cross-coupling; 48 h;
参考文献
Gavryushin, Andrei; Kofink, Christiane; Manolikakes, Georg; Knochel, Paul
Tetrahedron, 2006 , vol. 62, # 32 p. 7521 - 7533
反应条件
[(P{(NC5H10)(C6H11)2})2Pd(Cl)2] in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=100°C; Negishi cross-coupling reaction; 0.25 h; In air;
参考文献
Bolliger, Jeanne L.; Frech, Christian M.
Chemistry - A European Journal, 2010 , vol. 16, # 36 p. 11072 - 11081
反应条件
potassium phosphate; Ni(PCy3)2Cl2 in toluene T=180°C; Suzuki-Miyaura cross-coupling; 0.166667 h; Microwave irradiationInert atmosphere;
参考文献
Baghbanzadeh, Mostafa; Pilger, Christian; Kappe, C. Oliver
Journal of Organic Chemistry, 2011 , vol. 76, # 5 p. 1507 - 1510
反应条件
C32H26ClN2NiP in tetrahydrofuran; 1-methyl-pyrrolidin-2-one T=85°C; 12 h; Inert atmosphere;
参考文献
Zhang, Xue-Qi; Wang, Zhong-Xia
Journal of Organic Chemistry, 2012 , vol. 77, # 7 p. 3658 - 3663
反应条件
lithium chloride in tetrahydrofuran; toluene T=110°C; 24 h; Schlenk techniqueInert atmosphere;
参考文献
Shirakawa, Eiji; Tamakuni, Fumiko; Kusano, Eugene; Uchiyama, Nanase; Konagaya, Wataru; Watabe, Ryo; Hayashi, Tamio
Angewandte Chemie - International Edition, 2014 , vol. 53, # 2 p. 521 - 525
Angew. Chem., 2014 , vol. 126, # 2 p. 531 - 535,5
反应条件
pyridine; tetra-n-butylammonium tetrafluoroborate in acetonitrile T=20°C; Electrolysisiron rod as anode; stainless steel grid as cathode;
参考文献
Gomes, Paulo; Fillon, Hyacinthe; Gosmini, Corinne; Labbe, Eric; Perichon, Jacques
Tetrahedron, 2002 , vol. 58, # 42 p. 8417 - 8424
反应条件
tetrabutyl ammonium fluoride; bis(dibenzylideneacetone)-palladium(0); 2-dicyclohexylphosphino-1,1'-biphenyl in tetrahydrofuran 6 h; Heating;
参考文献
Seganish, W. Michael; DeShong, Philip
Journal of Organic Chemistry, 2004 , vol. 69, # 4 p. 1137 - 1143
反应条件
tris-(dibenzylideneacetone)dipalladium(0); KF dihydrate; [HP(t-Bu)3]BF4 in tetrahydrofuran T=20°C; Suzuki cross-coupling; Inert atmosphere;
参考文献
Lou, Sha; Fu, Gregory C.
Advanced Synthesis and Catalysis, 2010 , vol. 352, # 11-12 p. 2081 - 2084
