乙基2-[乙氧基(氧代)乙酰基]苯甲酸酯合成路线 (共 2 条)
反应条件
bis(acetylacetonate)nickel(II) in tetrahydrofuran T=20°C; Negishi coupling reaction; 0.166667 h;
参考文献
Kim, Seung-Hoi; Rieke, Reuben D.
Tetrahedron Letters, 2011 , vol. 52, # 13 p. 1523 - 1526
反应条件
1: 2-Iodo-benzoic acid ethyl ester With phenyllithium in diethyl ether; cyclohexane T=-60°C; 1.13889E-05 h; Flow reactor; 2: oxalic acid diethyl ester in diethyl ether; cyclohexane T=-60°C; 0.000466667 h; Flow reactor; 3: With water; acetic acid in tetrahydrofuran; hexane Temperature;
参考文献
Nagaki, Aiichiro; Ichinari, Daisuke; Yoshida, Jun-Ichi
Chemical Communications, 2013 , vol. 49, # 31 p. 3242 - 3244