N,N-二甲基- 3-羧基苯磺酰胺合成路线 (共 3 条)
反应条件
1: in tetrahydrofuran; dichloromethane 0.5 h; 2: With hydrogenchloride in tetrahydrofuran; dichloromethane; water
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2007/71963 A2, 2007 ;
Location in patent: Page/Page column 50 ;
WO 2007/071963 A2
反应条件
1: HClSO3 View Scheme
参考文献
Tetrahedron, , vol. 60, # 17 p. 3755 - 3762
反应条件
1: HCl gas / Heating
2: hydrazine hydrate / Heating
View Scheme
参考文献
Sorna, Venkataswamy; Theisen, Emily R.; Stephens, Bret; Warner, Steven L.; Bearss, David J.; Vankayalapati, Hariprasad; Sharma, Sunil
Journal of Medicinal Chemistry, 2013 , vol. 56, # 23 p. 9496 - 9508