(E,E)-11,13-十六碳二烯醛合成路线 （共 16 条）
反应条件
1: 29.4 g / xylene / 36 h / 80 °C
2: n-BuLi / tetrahydrofuran / 0.5 h
3: 5.4 g / tetrahydrofuran / 3 h / 60 °C
4: 86 percent / pyridinium chlorochromate, NaOAc / CH2Cl2 / 2 h / Ambient temperature
View Scheme
参考文献
Lo, Veng Meng; Shiao, Min-Jen
Synthetic Communications, 1986 , vol. 16, # 13 p. 1647 - 1656
反应条件
1: n-BuLi / tetrahydrofuran / 0.5 h
2: 5.4 g / tetrahydrofuran / 3 h / 60 °C
3: 86 percent / pyridinium chlorochromate, NaOAc / CH2Cl2 / 2 h / Ambient temperature
View Scheme
参考文献
Lo, Veng Meng; Shiao, Min-Jen
Synthetic Communications, 1986 , vol. 16, # 13 p. 1647 - 1656
反应条件
1: potassium 3-aminopropylamide, trimethylenediamine
2: aq. acid / diethyl ether
3: 1.) (C2H5)2ZrHCl, 2.) I2 / 1.) benzene, 2.) benzene
4: 1.) (C2H5)2ZrHCl, 2.) Pd(PPh3)4 / 1.) benzene, 2.) THF
5: aq. acid / methanol
6: PCC / CH2Cl2
View Scheme
参考文献
Arai, Koshi; Ando, Tetsu; Sakurai, Akira; Yamada, Hideo; Koshihara, Tatsuo; Takahashi, Nobutaka
Agricultural and Biological Chemistry, 1982 , vol. 46, # 9 p. 2395 - 2398
反应条件
1: BuLi / tetrahydrofuran; hexamethylphosphoric acid triamide
2: aq. acid / methanol
3: potassium 3-aminopropylamide, trimethylenediamine
4: aq. acid / diethyl ether
5: 1.) (C2H5)2ZrHCl, 2.) I2 / 1.) benzene, 2.) benzene
6: 1.) (C2H5)2ZrHCl, 2.) Pd(PPh3)4 / 1.) benzene, 2.) THF
7: aq. acid / methanol
8: PCC / CH2Cl2
View Scheme
参考文献
Arai, Koshi; Ando, Tetsu; Sakurai, Akira; Yamada, Hideo; Koshihara, Tatsuo; Takahashi, Nobutaka
Agricultural and Biological Chemistry, 1982 , vol. 46, # 9 p. 2395 - 2398
反应条件
1: aq. acid / diethyl ether
2: 1.) (C2H5)2ZrHCl, 2.) I2 / 1.) benzene, 2.) benzene
3: 1.) (C2H5)2ZrHCl, 2.) Pd(PPh3)4 / 1.) benzene, 2.) THF
4: aq. acid / methanol
5: PCC / CH2Cl2
View Scheme
参考文献
Arai, Koshi; Ando, Tetsu; Sakurai, Akira; Yamada, Hideo; Koshihara, Tatsuo; Takahashi, Nobutaka
Agricultural and Biological Chemistry, 1982 , vol. 46, # 9 p. 2395 - 2398
反应条件
1: aq. acid / methanol
2: PCC / CH2Cl2
View Scheme
参考文献
Arai, Koshi; Ando, Tetsu; Sakurai, Akira; Yamada, Hideo; Koshihara, Tatsuo; Takahashi, Nobutaka
Agricultural and Biological Chemistry, 1982 , vol. 46, # 9 p. 2395 - 2398
