1,4-diaza-bicyclo[2.2.2]octane in acetonitrile 16 h; Heating;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1731136', constants.ctx, '0')">trimethylsilyl iodide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '107477', constants.ctx, '0')">quinoline</a> <br />T=175&deg;C;&nbsp;0.0333333&nbsp;h;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342937', constants.ctx, '0')">potassium hydroxide</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br />1&nbsp;h;&nbsp;&nbsp;Heating;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 3 steps<br /> </b>1: 79 percent / tetrahydrofuran / 4 h / Heating<br />2: 93 percent / AlCl₃ / CH₂Cl₂ / 1 h / Ambient temperature<br />3: 92 percent / KOH / ethanol / 1 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 93 percent / AlCl₃ / CH₂Cl₂ / 1 h / Ambient temperature<br />2: 92 percent / KOH / ethanol / 1 h / Heating<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 84 percent / 3 N aq. HCl / 7 h / Heating<br />2: 79 percent / tetrahydrofuran / 4 h / Heating<br />3: 93 percent / AlCl₃ / CH₂Cl₂ / 1 h / Ambient temperature<br />4: 92 percent / KOH / ethanol / 1 h / Heating<br /> <br /> &nbsp;