1: pyridine 2: glacial acetic acid; palladium/barium sulfate / Hydrogenation 3: aqueous NaOH View Scheme

AzBTS; laccase in water Product distribution;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '10512883', constants.ctx, '0')">Grubb's 2nd generation catalyst</a>&nbsp;<b>in</b>&nbsp; neat (no solvent)<br />T=90&deg;C;&nbsp;1.33333&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;&nbsp;Reagent/catalystTemperature;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3903207', constants.ctx, '0')">titanium tetrachloride</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4948473', constants.ctx, '0')">magnesium</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102391', constants.ctx, '0')">tetrahydrofuran</a> <br />McMurry Reaction;&nbsp;3&nbsp;h;&nbsp;&nbsp;RefluxSchlenk technique;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '102438', constants.ctx, '0')">piperidine</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '11604118', constants.ctx, '0')">tetrakis(triphenylphosphine) palladium⁽⁰⁾</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '8127934', constants.ctx, '0')">lithium chloride</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1737614', constants.ctx, '0')">N,N-dimethyl acetamide</a> <br />T=160&deg;C;&nbsp;Heck Reaction;&nbsp;0.666667&nbsp;h;&nbsp;&nbsp;Microwave irradiation;&nbsp;<br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '4122946', constants.ctx, '0')">nickel</a> <br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: zinc; NH₄Cl; aqueous ethanol<br />2: Raney nickel; aqueous NaOH<br /> <br /> &nbsp;