反应条件
1: 67 percent / HBr / petroleum ether / 0.75 h / 15 °C
2: SOCl2
4: 1) NaOEt, 2) NaH / 1) reflux, 6 h, 2) toluene, reflux, 40 h
5: 1) NaoH, 2) HCl / ethanol / 24 h / Heating
6: 1.42 h / 160 °C
7: 69 percent / 0.38 N HCl / 1 h / Ambient temperature
8: 1) Ag2O, MeOH, 2) Br2, 3) Zn / 2) CCl4, 3) HOAc, reflux, 2 h
9: alkalin
View Scheme
参考文献
Tsai, K. R.; Newman, Melvin S.
Journal of Organic Chemistry, 1980 , vol. 45, # 23 p. 4785 - 4786
