(4-溴丁基)三苯基溴化膦合成路线 （共 15 条）
反应条件
in toluene T=80°C; 18 h;
参考文献
Schmidbaur, Hubert; Schier, Annette; Neugebauer, Dietmar
Chemische Berichte, 1983 , vol. 116, # 6 p. 2173 - 2179
反应条件
potassium tert-butylate 1.) Et2O, reflux, 3 h, 2.) Et2O, reflux, 1 h; Yield given. Multistep reaction;
参考文献
Fitjer, Lutz; Majewski, Marita; Monzo-Oltra, Honorato
Tetrahedron, 1995 , vol. 51, # 32 p. 8835 - 8852
反应条件
sodium hydrogensulfide; IRA-400 resin; ammonium chloride in methanol T=20°C; 18 h;
参考文献
Mehiri, Mohamed; Caldarelli, Sergio; Giorgio, Audrey Di; Barouillet, Thibault; Doglio, Alain; Condom, Roger; Patino, Nadia
Bioorganic Chemistry, 2007 , vol. 35, # 4 p. 313 - 326
反应条件
1: NaH / tetrahydrofuran; dimethylformamide 2: aq. NaOH View Scheme
参考文献
Schweizer,E.E. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 8 p. 3082 - 3088
参考文献
Mondon
Justus Liebigs Annalen der Chemie, 1957 , vol. 603, p. 115,127
Full Text Show Details
Dicker; Whitting
Journal of the Chemical Society, 1958 , p. 1994,1999
参考文献
Schweizer,E.E. et al.
Journal of Organic Chemistry, 1968 , vol. 33, # 8 p. 3082 - 3088
反应条件
in water; acetone
15 h; Heating;
参考文献
Hercouet, A.; Corre Le, M.
Tetrahedron, 1981 , vol. 37, # 16 p. 2861 - 2866
反应条件
1: 99 percent / dimethylformamide / 4 h / Heating
2: 98 percent / 20percent aqueous sodium hydroxide / 1 h / Heating
3: 1.) trichlorosilane, triethylamine 2.) 50percent aqueous sodium hydroxide / 1.) toluene, 5 min then reflux, 2 h 2.) toluene, ice cooling, 1 h
View Scheme
参考文献
Benn, Roger F.; Briggs, Josie C.; McAuliffe, Charles A.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1984 , p. 293 - 296
反应条件
1: 94 percent / dimethylformamide / 4 h / Heating
2: 85 percent / 20percent aqueous sodium hydroxide / 1 h / Heating
3: 1.) trichlorosilane, triethylamine 2.) 50percent aqueous sodium hydroxide / 1.) toluene, 5 min then reflux, 2 h 2.) toluene, ice cooling, 1 h
View Scheme
参考文献
Benn, Roger F.; Briggs, Josie C.; McAuliffe, Charles A.
Journal of the Chemical Society, Dalton Transactions: Inorganic Chemistry (1972-1999), 1984 , p. 293 - 296
反应条件
in methanol; water
T=80°C; 18 h; Sealed tube;
参考文献
Deane, Karen J.; Summers, Robert L.; Lehane, Adele M.; Martin, Rowena E.; Barrow, Russell A.
ACS Medicinal Chemistry Letters, 2014 , vol. 5, # 5 p. 576 - 581
