乙基5-氨基-2-甲基苯甲酸酯合成路线 （共 5 条）
反应条件
1: With hydrogen bromide in water Cooling with ice; 2: With hydrogen bromide; sodium nitrite in water 3: With hydrogen bromide; copper(I) bromide in water T=70°C; Cooling with ice;
参考文献
The Government of the United States of America, as represented by the Secretary, Department of HHS; Albany Molecular Research, Inc.; Science Applications International Corporation
Patent: US2009/312323 A1, 2009 ;
Location in patent: Page/Page column 13 ;
反应条件
1: With sulfuric acid in water T=0°C; 0.25 h; 2: With sulfuric acid; water; sodium nitrite T=0 - 60°C; 18.5 h;
参考文献
The Government of the United States of America, as represented by the Secretary, Department of HHS; Albany Molecular Research, Inc.; Science Applications International Corporation
Patent: US2009/312323 A1, 2009 ;
Location in patent: Page/Page column 17 ;
反应条件
hydrogen; palladium on activated charcoal in ethanol
Ambient temperature;
参考文献
Della Sala, Giorgio; Izzo, Irene; De Riccardis, Francesco; Sodano, Guido
Tetrahedron Letters, 1998 , vol. 39, # 26 p. 4741 - 4744
反应条件
1: 94 percent / H2SO4
2: 100 percent / H2 / Pd/C / ethanol / Ambient temperature
View Scheme
参考文献
Della Sala, Giorgio; Izzo, Irene; De Riccardis, Francesco; Sodano, Guido
Tetrahedron Letters, 1998 , vol. 39, # 26 p. 4741 - 4744
反应条件
tert.-butylnitrite; iodine in toluene
T=0 - 20°C;
参考文献
GLAXO GROUP LIMITED
Patent: WO2003/84917 A1, 2003 ;
Location in patent: Page/Page column 63 ;
