1: H2 / 5percent Pd/C / ethanol 2: 89 percent / NaOAc 3: 67 percent / NaOCH3 / ethanol / 1 h / Heating 4: 91 percent / SOCl2/DMF / CHCl3 / 0.5 h / 50 °C 5: 2 h / 130 °C View Scheme

hydrogen bromide; acetic acid 24 h; Inert atmosphereSchlenk techniqueReflux;