6-甲基-2,4-二苯基喹啉合成路线 （共 23 条）
反应条件
DPDC in benzene
T=60°C; 5 h;
参考文献
Leardini, Rino; Nanni, Daniele; Pedulli, Gian Franco; Tundo, Antonio; Zanardi, Giuseppe
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1591 - 1594
反应条件
hydrogen bromide in nitromethane
1) R.T., 15 min 2) 40 deg C, 0.5 h;
参考文献
Cacchi, S.; Palmieri, G.
Tetrahedron, 1983 , vol. 39, # 20 p. 3373 - 3384
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane
T=120°C; Inert atmosphereSealed tube; regioselective reaction;
参考文献
Wang, Yong; Chen, Chao; Peng, Jing; Li, Ming
Angewandte Chemie - International Edition, 2013 , vol. 52, # 20 p. 5323 - 5327
Angew. Chem., 2013 , vol. 125, # 20 p. 5431 - 5435,5
反应条件
titanium(IV) isopropylate in dichloromethane
T=20°C; photosensitized imino Diels-Alder reaction; 24 h; Irradiation;
参考文献
Zhang, Wei; Jia, Xiaodong; Yang, Li; Liu, Zhong-Li
Tetrahedron Letters, 2002 , vol. 43, # 51 p. 9433 - 9436
反应条件
di-isopropylperoxydicarbonate in benzene
T=60°C; 4 h;
参考文献
Leardini, Rino; Nanni, Daniele; Tundo, Antonio; Zanardi, Giuseppe
Gazzetta Chimica Italiana, 1989 , vol. 119, # 12 p. 637 - 642
反应条件
1: 85 percent / TBA(+)Cl(-) / PdCl2 / CH2Cl2; aq. HCl / 9 h / Ambient temperature
2: 82 percent / HBr / nitromethane / 1) R.T., 15 min 2) 40 deg C, 0.5 h
View Scheme
参考文献
Cacchi, S.; Palmieri, G.
Tetrahedron, 1983 , vol. 39, # 20 p. 3373 - 3384
反应条件
2,3-dicyano-5,6-dichloro-p-benzoquinone in acetonitrile
0.75 h; Heating;
参考文献
Bortolotti; Leardini; Nanni; Zanardi
Tetrahedron, 1993 , vol. 49, # 44 p. 10157 - 10174
反应条件
in tetrahydrofuran
4 h; Ambient temperatureIrradiationfurther solvents benzene, toluene;
参考文献
Campos, Pedro J.; Tan, Cheng-Quan; Rodriguez, Miguel A.; Anon, Elena
Journal of Organic Chemistry, 1996 , vol. 61, # 20 p. 7195 - 7197
反应条件
1.) benzene, RT, irradiation, 2.) reflux; Yield given. Multistep reaction;
参考文献
Nishio, Takehiko; Omote, Yoshimori
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 8 p. 1773 - 1775
反应条件
1: 0.17 h
2: trifluorormethanesulfonic acid; AgNTf2 / toluene / 24 h / 80 °C
View Scheme
参考文献
Zhang, Xu; Liu, Baoqing; Shu, Xin; Gao, Yang; Lv, Haipeng; Zhu, Jin
Journal of Organic Chemistry, 2012 , vol. 77, # 1 p. 501 - 510
