反应条件
1: 90 percent / PBr3 / diethyl ether / 0 °C
2: 99 percent / NaH / tetrahydrofuran / 0 deg C -> room temperature
3: 1.) Ba(OH)2 / 2.) H2O, Et2O, 90 deg C, 17 h
4: LAH / diethyl ether / 0 °C
5: 1.) PBr3, LiBr, collidine, 2.) ZnBr2 / 1.) Et2O, -40 - 0 deg C, 2.) 0 deg C
6: 90 percent / LiH / dimethylformamide / 75 °C
7: SnCl4 / CH2Cl2 / 1.5 h / 0 °C
8: MeSO2Cl, (C2H5)3N / CH2Cl2 / 0 °C
9: m-ClC6H4CO3H / CH2Cl2 / Ambient temperature
10: n-C4H9Li, (i-C3H7)NH / CH2Cl2 / -78 °C
View Scheme
参考文献
Van Tamelen; Leiden
Journal of the American Chemical Society, 1982 , vol. 104, # 6 p. 1785 - 1786
