N-苯基-4-哌啶甲酰胺盐酸盐合成路线 (共 7 条)
反应条件
trifluoroacetic acid T=20°C; 24 h;
参考文献
Journal of Medicinal Chemistry, , vol. 52, # 17 p. 5380 - 5393
反应条件
hydrogen; platinum(IV) oxide in acetic acid T=30°C; P=2585.7 Torr;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 6 p. 999 - 1003
反应条件
potassium hydroxide; nickel monoaluminide in methanol 18.1 h; Heating;
参考文献
Lunn, George; Sansone, Eric B.
Journal of Organic Chemistry, 1986 , vol. 51, # 4 p. 513 - 517
反应条件
1: 0.6 g / 2 h / Heating 2: thionyl chloride / 2 h / Heating 3: 0.7 g / CHCl3 / 2 h / Ambient temperature 4: 200 mg / 10percent aq. NaOH / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 17 p. 2519 - 2525
反应条件
1: thionyl chloride / 2 h / Heating 2: 0.7 g / CHCl3 / 2 h / Ambient temperature 3: 200 mg / 10percent aq. NaOH / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 17 p. 2519 - 2525
反应条件
1: 0.7 g / CHCl3 / 2 h / Ambient temperature 2: 200 mg / 10percent aq. NaOH / 2 h / Ambient temperature View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 36, # 17 p. 2519 - 2525
反应条件
1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / dichloromethane / 18 h / 20 °C 2: hydrogenchloride / ethyl acetate; water / 2 h / 20 °C View Scheme
参考文献
European Journal of Medicinal Chemistry, , vol. 71, p. 259 - 266