6-(叔-丁基二甲基硅烷基氧基)-1-己炔合成路线 （共 22 条）
反应条件
1: TBAF; HOAc / tetrahydrofuran
2: Dess-Martin reagent
View Scheme
参考文献
Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav
Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482
反应条件
1: TBAF; HOAc / tetrahydrofuran
2: Dess-Martin reagent
View Scheme
参考文献
Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav
Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482
反应条件
1: TBAF; HOAc / tetrahydrofuran
2: Dess-Martin reagent
View Scheme
参考文献
Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav
Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482
反应条件
1: TBAF; HOAc / tetrahydrofuran
2: Dess-Martin reagent
View Scheme
参考文献
Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav
Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482
反应条件
1: TBAF; HOAc / tetrahydrofuran
2: Dess-Martin reagent
View Scheme
参考文献
Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav
Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482
反应条件
1: LDA
2: CuBr2
3: TBAF; HOAc / tetrahydrofuran
4: Dess-Martin reagent
View Scheme
参考文献
Moore, Jennifer L.; Kerr, Mark S.; Rovis, Tomislav
Tetrahedron, 2006 , vol. 62, # 49 p. 11477 - 11482
反应条件
1: 1.) sec-BuLi, HMPA / 1.) THF, -78 deg C, 2.) THF, from -78 deg C to RT, 2 h
2: tetra-n-butylammonium fluoride / tetrahydrofuran / 1 h / Ambient temperature
View Scheme
参考文献
Krafft, Marie E.; Scott, Ian L.; Romero, Romulo H.; Feibelmann, Sabine; Van Pelt, Craig E.
Journal of the American Chemical Society, 1993 , vol. 115, # 16 p. 7199 - 7207
反应条件
Schwartz's reagent in toluene
T=20°C; Hydrogenation; 12 h;
参考文献
Evans, David A.; Barnes, David M.; Johnson, Jeffrey S.; Lectka, Thomas; Von Matt, Peter; Miller, Scott J.; Murry, Jerry A.; Norcross, Roger D.; Shaughnessy, Eileen A.; Campos, Kevin R.
Journal of the American Chemical Society, 1999 , vol. 121, # 33 p. 7582 - 7594
反应条件
1: 86 percent / Cs2CO3; N,N-dimethylglycine / CuI / dioxane / 80 °C
2: 95 percent / PPh3; phenol / benzene / 50 °C
3: TBAF / tetrahydrofuran
4: Et3N; DMAP
5: NaN3 / dimethylformamide
View Scheme
参考文献
Yu, Shouyun; Liu, Feng; Ma, Dawei
Tetrahedron Letters, 2006 , vol. 47, # 51 p. 9155 - 9157
反应条件
1: 1) n-BuLi, 2) 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone / 1) THF, hexane, -10 deg C, 0.5h. 2a) -10 deg C, 0.5h, 2b) RT, 1h
2: 550 mg / Bu4NF / tetrahydrofuran / 48 h / Ambient temperature
View Scheme
参考文献
Torisawa; Hashimoto; Nakagawa; Seki; Hara; Hino
Tetrahedron, 1991 , vol. 47, # 38 p. 8067 - 8078
