palladium 10 on activated carbon; hydrogen in pentane T=20°C; 3 h;

CuSPh; methanesulfonyl chloride; triethylamine; phosphorous acid trimethyl ester 1.) CH2Cl2, 0 deg C, 2.) 0 deg C, 5 min; Yield given. Multistep reaction;

1: 1.) Tf2O, Et3N, 2.) PhSCu.P(OMe)3 / 1.) CH2Cl2, -78 deg C, 2.) -78 -> 0 deg C 2: mCPBA / CH2Cl2 / 0 - 20 °C View Scheme