5-溴-2,4-二羟基苯酸合成路线 （共 24 条）
反应条件
trifluoroacetic anhydride in trifluoroacetic acid
T=0 - 25°C; 10 h;
参考文献
Tisdale, Eric J.; Vong, Binh G.; Li, Hongmei; Kim, Sun Hee; Chowdhury, Chinmay; Theodorakis, Emmanuel A.
Tetrahedron, 2003 , vol. 59, # 35 p. 6873 - 6887
反应条件
1.1: 61 percent / TFA; TFAA / 10 h / 0 - 25 °C
2.1: K2CO3; KI; CuI / acetone / 1 h / Heating
2.2: 90 percent / acetone; dimethylformamide / 15 h / 150 °C
View Scheme
参考文献
Tisdale, Eric J.; Li, Hongmei; Vong, Binh G.; Kim, Sun Hee; Theodorakis, Emmanuel A.
Organic Letters, 2003 , vol. 5, # 9 p. 1491 - 1494
反应条件
sodium hydroxide
T=60 - 70°C;
参考文献
Rice
Journal of the American Chemical Society, 1926 , vol. 48, p. 3127
参考文献
Rice
Journal of the American Chemical Society, 1926 , vol. 48, p. 3127
