2-氨基-4-羟基吡咯并[2,3-d]嘧啶合成路线

参考文献

Akimoto, Hiroshi; Imamiya, Eiko; Hitaka, Takenori; Nomura, Hiroaki; Nishimura, Susumu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1637 - 1644

108-24-7乙酸酐+

7355-55-72-氨基-4-羟基吡咯并[2,3-d]嘧啶

88062-66-2

参考文献

Benghiat, Eric; Crooks, Peter A.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1023 - 1025

7355-55-72-氨基-4-羟基吡咯并[2,3-d]嘧啶+

77-78-1硫酸二甲酯

90065-67-12-氨基-3,7-二氢-3-甲基-4H-吡咯并[2,3-d]嘧啶-4-酮

参考文献

Seela; Bussmann; Gotze; Rosemeyer
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 981 - 985

7355-55-72-氨基-4-羟基吡咯并[2,3-d]嘧啶

911397-54-14-氯-5-碘-7-(4-甲氧基-3,5-二甲基吡啶-2-甲基)-7H-吡咯并[2,3-d]嘧啶-2-胺

参考文献

Shi, Jiandong; Van De Water, Ryan; Hong, Kevin; Lamer, Ryan B.; Weichert, Kenneth W.; Sandoval, Cristina M.; Kasibhatla, Srinivas R.; Boehm, Marcus F.; Chao, Jianhua; Lundgren, Karen; Timple, Noelito; Lough, Rachel; Ibanez, Gerardo; Boykin, Christina; Burrows, Francis J.; Kehry, Marilyn R.; Yun, Theodore J.; Harning, Erin K.; Ambrose, Christine; Thompson, Jeffrey; Bixler, Sarah A.; Dunah, Anthone; Snodgrass-Belt, Pamela; Arndt, Joseph; Enyedy, Istvan J.; Li, Ping; Hong, Victor S.; McKenzie, Andres; Biamonte, Marco A.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7786 - 7795

7355-55-72-氨基-4-羟基吡咯并[2,3-d]嘧啶+

75-36-5乙酰氯

62160-25-2N-(4-氧代-1,7-二氢吡咯并[2,3-d]嘧啶-2-基)乙酰胺

参考文献

Akimoto, Hiroshi; Imamiya, Eiko; Hitaka, Takenori; Nomura, Hiroaki; Nishimura, Susumu
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 1637 - 1644

7355-55-72-氨基-4-羟基吡咯并[2,3-d]嘧啶

62160-25-2N-(4-氧代-1,7-二氢吡咯并[2,3-d]嘧啶-2-基)乙酰胺

参考文献

Benghiat, Eric; Crooks, Peter A.
Journal of Heterocyclic Chemistry, 1983 , vol. 20, p. 1023 - 1025