2-氮杂双环[2.1.1]己烷-1-羧酸盐酸盐合成路线 （共 9 条）
反应条件
hydrogenchloride in water 15 h; Heating;
参考文献
Hughes, Philip; Clardy, Jon
Journal of Organic Chemistry, 1988 , vol. 53, # 20 p. 4793 - 4797
反应条件
1: Zn; AcOH / 4 h / Heating 2: 85 percent / NH4Cl; aq. (NH4)2CO3 / acetonitrile / 50 °C 3: 100 percent / aq. NaOH / 24 h / Heating 4: aq. HBr / 1 h / Heating 5: 73 percent / aq. HBr / 6 h / Heating 6: NaOH / 1.5 h / Heating View Scheme
参考文献
Chemical Communications, , # 3 p. 250 - 251
反应条件
1: 85 percent / NH4Cl; aq. (NH4)2CO3 / acetonitrile / 50 °C 2: 100 percent / aq. NaOH / 24 h / Heating 3: aq. HBr / 1 h / Heating 4: 73 percent / aq. HBr / 6 h / Heating 5: NaOH / 1.5 h / Heating View Scheme
参考文献
Chemical Communications, , # 3 p. 250 - 251
反应条件
1: 87 percent / acetophenone / benzene / 12 h / Ambient temperature; Irradiation 2: 98 percent / 6 N HCl / H2O / 15 h / Heating View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 20 p. 4793 - 4797
反应条件
in potassium hydroxide Heating;
参考文献
Pirrung, Michael C.
Tetrahedron Letters, 1980 , vol. 21, # 48 p. 4577 - 4578
反应条件
1: 100 percent / aq. NaOH / 24 h / Heating 2: aq. HBr / 1 h / Heating 3: 73 percent / aq. HBr / 6 h / Heating 4: NaOH / 1.5 h / Heating View Scheme
参考文献
Chemical Communications, , # 3 p. 250 - 251
反应条件
1: diethyl ether / Irradiation 2: 72 percent / aq. KOH / Heating View Scheme
参考文献
Tetrahedron Letters, , vol. 21, # 48 p. 4577 - 4578
反应条件
sodium hydroxide in water; tert-butyl alcohol 24 h; Ambient temperature;
参考文献
Hughes, Philip; Clardy, Jon
Journal of Organic Chemistry, 1988 , vol. 53, # 20 p. 4793 - 4797
反应条件
1: NaOH / H2O; 2-methyl-propan-2-ol / 24 h / Ambient temperature 2: CH2Cl2 3: 66 percent / sodium m-periodate, ruthenium dioxide / acetonitrile; H2O; CCl4 / 504 h 4: thionyl chloride, HCl gas / CH2Cl2 / 1 h 5: 80 percent / Et3N / CH2Cl2 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 20 p. 4793 - 4797
