2-(2-溴苯基)-1,3-苯并恶唑合成路线 （共 10 条）
反应条件
NiII chloride hexahydrate; tetrabutyl ammonium fluoride; potassium carbonate; palladium dichloride in N,N-dimethyl-formamide T=100°C; Suzuki-Miyaura Coupling; 2 h;
参考文献
Seth, Kapileswar; Purohit, Priyank; Chakraborti, Asit K.
Organic Letters, 2014 , vol. 16, # 9 p. 2334 - 2337
反应条件
Na8H[PW9O34]*7H2O in acetonitrile
T=25°C; 6 h;
参考文献
Zhao, Shen; Chen, Yang; Song, Yu-Fei
Applied Catalysis A: General, 2014 , vol. 475, p. 140 - 146
反应条件
methanesulfonic acid in 1,4-dioxane
T=100°C; 2 h; chemoselective reaction;
参考文献
Kumar, Dinesh; Rudrawar, Santosh; Chakraborti, Asit K.
Australian Journal of Chemistry, 2008 , vol. 61, # 11 p. 881 - 887
反应条件
oxygen; copper(II) bis(trifluoromethanesulfonate) in toluene
T=80°C; 1 h;
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
反应条件
iodine; N,N-dimethyl-formamide in chlorobenzene
T=130°C;
参考文献
Teo, Yew Chin; Riduan, Siti Nurhanna; Zhang, Yugen
Green Chemistry, 2013 , vol. 15, # 9 p. 2365 - 2368
反应条件
1: sulfuryl dichloride / toluene / 1 h / 80 °C
2: methanesulfonic acid / 1,4-dioxane / 5 h / 100 °C
View Scheme
参考文献
Seth, Kapileswar; Purohit, Priyank; Chakraborti, Asit K.
Organic Letters, 2014 , vol. 16, # 9 p. 2334 - 2337
反应条件
1: hydrazine / methanol; chloroform; water / 12 h / 20 °C
2: acetic acid / water / 0.5 h / 20 °C
3: oxygen; copper(II) bis(trifluoromethanesulfonate) / toluene / 1 h / 80 °C
View Scheme
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
反应条件
1: acetic acid / water / 0.5 h / 20 °C
2: oxygen; copper(II) bis(trifluoromethanesulfonate) / toluene / 1 h / 80 °C
View Scheme
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
反应条件
1: pyridine; copper(I) bromide / dichloromethane / 48 h / 20 °C / Molecular sieve
2: hydrazine / methanol; chloroform; water / 12 h / 20 °C
3: acetic acid / water / 0.5 h / 20 °C
4: oxygen; copper(II) bis(trifluoromethanesulfonate) / toluene / 1 h / 80 °C
View Scheme
参考文献
Guru, Murali Mohan; Ali, Md Ashif; Punniyamurthy, Tharmalingam
Journal of Organic Chemistry, 2011 , vol. 76, # 13 p. 5295 - 5308
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in tetrahydrofuran; water
Inert atmosphereSchlenk technique;
参考文献
Rao, Ying-Li; Amarne, Hazem; Chen, Leanne D.; Brown, Matthew L.; Mosey, Nicholas J.; Wang, Suning
Journal of the American Chemical Society, 2013 , vol. 135, # 9 p. 3407 - 3410
