hydrogen; platinum in ethyl acetate 6 h;

1: 1.) CH3COOH, 2.) conc HCl / 1.) 1.5 h, 2.) reflux, 5 h 2: oxalyl chloride / benzene / 33 h / 55 °C 3: 93 percent / NH3 / CHCl3 / 0.5 h / 0 °C 4: 74 percent / trifluoroacetic anhydride, pyridine / tetrahydrofuran / 0.67 h / Ambient temperature 5: 81 percent / H2 / Pt / ethyl acetate / 6 h View Scheme

1: 93 percent / NH3 / CHCl3 / 0.5 h / 0 °C 2: 74 percent / trifluoroacetic anhydride, pyridine / tetrahydrofuran / 0.67 h / Ambient temperature 3: 81 percent / H2 / Pt / ethyl acetate / 6 h View Scheme

1: oxalyl chloride / benzene / 33 h / 55 °C 2: 93 percent / NH3 / CHCl3 / 0.5 h / 0 °C 3: 74 percent / trifluoroacetic anhydride, pyridine / tetrahydrofuran / 0.67 h / Ambient temperature 4: 81 percent / H2 / Pt / ethyl acetate / 6 h View Scheme

1: 74 percent / trifluoroacetic anhydride, pyridine / tetrahydrofuran / 0.67 h / Ambient temperature 2: 81 percent / H2 / Pt / ethyl acetate / 6 h View Scheme

1: 1.) CH3COOH, 2.) conc HCl / 1.) 1.5 h, 2.) reflux, 5 h 2: oxalyl chloride / benzene / 33 h / 55 °C 3: 93 percent / NH3 / CHCl3 / 0.5 h / 0 °C 4: 74 percent / trifluoroacetic anhydride, pyridine / tetrahydrofuran / 0.67 h / Ambient temperature 5: 81 percent / H2 / Pt / ethyl acetate / 6 h View Scheme