2-[4-[(Z)-1-(4-氟苯基)-2-苯基丁-1-烯基]苯氧基]-N,N-二甲基乙胺合成路线 （共 13 条）
反应条件
1: 1.) Mg / 2.) ether, 2.) ether, reflux, 4 h
2: 85 percent / BBr3 / CH2Cl2 / 1 h / Ambient temperature
3: KOH / ethanol / 20 h / Heating
View Scheme
参考文献
Shani; Gazit; Livshitz; Biran
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1504 - 1511
反应条件
1: 85 percent / BBr3 / CH2Cl2 / 1 h / Ambient temperature
2: KOH / ethanol / 20 h / Heating
View Scheme
参考文献
Shani; Gazit; Livshitz; Biran
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1504 - 1511
反应条件
potassium hydroxide in ethanol
20 h; Heating; Title compound not separated from byproducts;
参考文献
Shani; Gazit; Livshitz; Biran
Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1504 - 1511
