1-甲基-1H-吡咯并[2,3-b]吡啶-5-醇合成路线 （共 3 条）
反应条件
boron tribromide in dichloromethane
T=0 - 20°C;
参考文献
Larraya, Carlos; Guillard, Jerome; Renard, Pierre; Audinot, Valerie; Boutin, Jean A.; Delagrange, Philippe; Bennejean, Caroline; Viaud-Massuard, Marie-Claude
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 6 p. 515 - 526
反应条件
1: copper(I) bromide / dimethylformamide; methanol / 2.5 h / Heating
2: 0.51 g / sodium hydride / dimethylformamide / 13 h / 0 - 20 °C
3: 85 percent / boron tribromide / CH2Cl2 / 0 - 20 °C
View Scheme
参考文献
Larraya, Carlos; Guillard, Jerome; Renard, Pierre; Audinot, Valerie; Boutin, Jean A.; Delagrange, Philippe; Bennejean, Caroline; Viaud-Massuard, Marie-Claude
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 6 p. 515 - 526
反应条件
1: 0.51 g / sodium hydride / dimethylformamide / 13 h / 0 - 20 °C
2: 85 percent / boron tribromide / CH2Cl2 / 0 - 20 °C
View Scheme
参考文献
Larraya, Carlos; Guillard, Jerome; Renard, Pierre; Audinot, Valerie; Boutin, Jean A.; Delagrange, Philippe; Bennejean, Caroline; Viaud-Massuard, Marie-Claude
European Journal of Medicinal Chemistry, 2004 , vol. 39, # 6 p. 515 - 526
