2-氟-1-(4-甲氧基苯基)乙酮合成路线 （共 18 条）
反应条件
1: 62 percent / H5IO6; pyridinium chlorochromate / acetonitrile / 2.5 h / 20 °C
2: 65 percent / Rongalite / ethanol / 0.75 h / Heating
View Scheme
参考文献
Barkakaty, Balaka; Takaguchi, Yutaka; Tsuboi, Sadao
Tetrahedron, 2007 , vol. 63, # 4 p. 970 - 976
反应条件
aluminium trichloride in chloroform
Ambient temperature;
参考文献
Eguchi; Aoyama; Kakinuma
Tetrahedron Letters, 1992 , vol. 33, # 38 p. 5545 - 5546
反应条件
pyridine hydrogenfluoride in diethyl ether
4 h; Ambient temperature; Yield given;
参考文献
Bridge, Colin F.; O'Hagan, David
Journal of Fluorine Chemistry, 1997 , vol. 82, # 1 p. 21 - 24
反应条件
1: diethyl ether
2: pyridinium poly(hydrogen fluoride) / diethyl ether / 4 h / Ambient temperature
View Scheme
参考文献
Bridge, Colin F.; O'Hagan, David
Journal of Fluorine Chemistry, 1997 , vol. 82, # 1 p. 21 - 24
反应条件
hydrogenchloride; sodium carbonate; N-fluorobislt;(trifluoromethyl)sulfonylgt;imide
1.) CH2Cl2, room temp., 5 h, 2.) CH2Cl2; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Ying; DesMarteau; Gotoh
Tetrahedron, 1996 , vol. 52, # 1 p. 15 - 22
反应条件
1: With methanol; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)
1 h; Microwave irradiation;
2: With water
0.25 h; Microwave irradiation;
参考文献
Krane Thvedt, Thor Hakon; Fuglseth, Erik; Sundby, Eirik; Hoff, Bard Helge
Tetrahedron, 2009 , vol. 65, # 46 p. 9550 - 9556
反应条件
1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)
48 h; Heating;
参考文献
Fuglseth, Erik; Thvedt, Thor Hakon Krane; Moll, Maria Forde; Hoff, Bard Helge
Tetrahedron, 2008 , vol. 64, # 30-31 p. 7318 - 7323
反应条件
1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)
1 h; Microwave irradiation;
参考文献
Krane Thvedt, Thor Hakon; Fuglseth, Erik; Sundby, Eirik; Hoff, Bard Helge
Tetrahedron, 2009 , vol. 65, # 46 p. 9550 - 9556
