[1-(叔丁基二甲基甲硅烷基氧基甲基)环丙基]甲醇合成路线 (共 2 条)
反应条件
1H-imidazole in dichloromethane
T=20°C; 3 h;
参考文献
Liu, Lian Jin; Kim, Eunae; Hong, Joon Hee
Nucleosides, Nucleotides and Nucleic Acids, 2011 , vol. 30, # 10 p. 784 - 797
反应条件
1: 1,1-dimethoxycyclopropane With sodium hydride in ethylene glycol dimethyl ether
T=20°C; 1 h;
2: tert-butyldimethylsilyl chloride in ethylene glycol dimethyl ether
T=20°C;
参考文献
Takeda Chemical Industries, Ltd.
Patent: EP1591446 A1, 2005 ;
Location in patent: Page/Page column 98 ;