1-甲氧基-4-苯基乙炔苯合成路线 （共 169 条）
反应条件
1: 85 percent / dimethylformamide / 16 h / 20 °C
2: 96 percent / Br2 / CH2Cl2 / 16 h
3: 50 percent / KOtBu / 2-methyl-propan-2-ol / 5 h / 50 °C
View Scheme
参考文献
Pati, Hari N.; Wicks, Martha; Holt Jr., Herman L.; LeBlanc, Regan; Weisbruch, Paul; Forrest, Lori; Lee, Moses
Heterocyclic Communications, 2005 , vol. 11, # 2 p. 117 - 120
反应条件
1: CuCl2*2H2O / aq. HCl
2: KOH / dioxane
View Scheme
参考文献
Dombrovskii,A.V.; Taschchuk,K.G.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 1 p. 165 - 170,158 - 162
反应条件
1: CuCl2*2H2O / aq. HCl
2: KOH / dioxane
View Scheme
参考文献
Dombrovskii,A.V.; Taschchuk,K.G.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 1 p. 165 - 170,158 - 162
反应条件
2: 95 percent / KOH
View Scheme
参考文献
Al-Hassan, Mohammed I.
Journal of Organometallic Chemistry, 1990 , vol. 395, # 2 p. 227 - 229
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran
T=20°C; 1 h; oth. phenylacetylides, oth. Pd catalysts, oth. time; Product distribution;
参考文献
Bumagin, N. A.; Ponomarev, A. B.; Beletskaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1987 , vol. 23, # 7 p. 1215 - 1222
Zhurnal Organicheskoi Khimii, 1987 , vol. 23, # 7 p. 1345 - 1353
反应条件
sodium hydride in dimethyl sulfoxide
T=0 - 20°C; 9 h; other reagent, solvent, reaction time, temperature; Product distribution;
参考文献
Muthiah; Kumar, K. Praveen; Kumaraswamy, Sudha; Kumara Swamy
Tetrahedron, 1998 , vol. 54, # 47 p. 14315 - 14326
反应条件
(i) nBuLi, (ii) /BRN= 1104713/; Multistep reaction;
参考文献
Colvin,E.W.; Hamill,B.D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1977 , p. 869 - 874
参考文献
Katritzky et al.
Journal of the Chemical Society, 1960 , p. 1516
反应条件
lithium iodide in 2,3,5-trimethyl-pyridine
参考文献
Hay; Allan S.; Paventi; Martino
Patent: US5233046 A1, 1993 ;
反应条件
formic acid; tributyl-amine; bis(acetato)bis(triphenylphosphine)palladium(0) in acetonitrile
T=80°C; 8 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Cacchi, Sandro; Felici, Marcello; Pietroni, Biancarosa
Tetrahedron Letters, 1984 , vol. 25, # 29 p. 3137 - 3140
