1-甲氧基-4-苯基乙炔苯合成路线 （共 169 条）
反应条件
complex of lt;PdCl(π-C3H5)gt;2 and N-(2-diphenylphosphinobenzylidene)-2-phenylethylamine in tetrahydrofuran
T=50°C; 29 h;
参考文献
Shirakawa, Eiji; Yoshida, Hiroto; Takaya, Hidemasa
Tetrahedron Letters, 1997 , vol. 38, # 21 p. 3759 - 3762
反应条件
1: para-iodoanisole; 2-methyl-but-3-yn-2-ol With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride in toluene
T=80°C; Sonogashira coupling; 1 h;
2: iodobenzene With sodium hydride
T=110°C; Sonogashira coupling;
参考文献
Novak, Zoltan; Nemes, Peter; Kotschy, Andras
Organic Letters, 2004 , vol. 6, # 26 p. 4917 - 4920
反应条件
tetrabutyl-ammonium chloride; silver carbonate; palladium diacetate; triphenylphosphine in tetrahydrofuran
T=60 - 65°C; Substitution; 2 h;
参考文献
Koseki, Yuji; Omino, Kunio; Anzai, Shinobu; Nagasaka, Tatsuo
Tetrahedron Letters, 2000 , vol. 41, # 14 p. 2377 - 2380
反应条件
copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in tetrahydrofuran
Negishi cross-coupling; Inert atmosphereReflux;
参考文献
Stefani, Helio A.; Pena, Jesus M.; Manarin, Flavia; Ando, Romulo A.; Leal, Daiana M.; Petragnani, Nicola
Tetrahedron Letters, 2011 , vol. 52, # 34 p. 4398 - 4401
反应条件
pyrrolidine; Najera palladacycle I; 4-laurylbenzenesulfonic acid sodium salt; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in water
T=130°C; Sonogashira Cross-Coupling; 0.5 h; Microwave irradiationSealed tubeGreen chemistry; chemoselective reaction;
参考文献
Buxaderas, Eduardo; Alonso, Diego A.; Najera, Carmen
European Journal of Organic Chemistry, 2013 , # 26 p. 5864 - 5870
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); potassium carbonate in dimethyl sulfoxide
T=150°C; Sonogashira coupling; 1 h; Microwave irradiationInert atmosphere;
参考文献
Kawaguchi, Shin-Ichi; Srivastava, Puneet; Engman, Lars
Tetrahedron Letters, 2011 , vol. 52, # 32 p. 4120 - 4122
反应条件
oxygen; palladium diacetate in tetrahydrofuran
T=25°C; Sonogashira coupling; P=760.051 Torr; 1.5 h;
参考文献
Pankajakshan, Sreekumar; Loh, Teck-Peng
Chemistry - An Asian Journal, 2011 , vol. 6, # 9 p. 2291 - 2295
反应条件
silver fluoride; potassium hydrogencarbonate; bis(dibenzylideneacetone)-palladium(0) in acetonitrile
T=20°C; Hiyama Coupling; 12 h;
参考文献
Tang, Jiansheng; Guo, Cancheng
Journal of Chemical Research, 2014 , vol. 38, # 2 p. 123 - 127
反应条件
lanthanum; iodine in tetrahydrofuran
T=67°C; Fritsch-Buttenberg-Wiechell rearrangement; 3 h; Inert atmosphere;
参考文献
Umeda, Rui; Yuasa, Takumi; Anahara, Namika; Nishiyama, Yutaka
Journal of Organometallic Chemistry, 2011 , vol. 696, # 9 p. 1916 - 1919
反应条件
1: methoxybenzene With air; Bi(NO3)3·5H2O; iodine; bismuth(III) chloride in acetonitrile
T=20°C; 6 h;
2: phenylacetylene With piperidine; bis-triphenylphosphine-palladium(II) chloride in acetonitrile
T=70°C; 3 h;
参考文献
Wan, Shun; Wang, Sunewang R.; Lu, Wenjun
Journal of Organic Chemistry, 2006 , vol. 71, # 11 p. 4349 - 4352
