1-甲氧基-4-苯基乙炔苯合成路线 （共 169 条）
反应条件
carbon monoxide; copper; zinc; bis(cyclopentadienyl)titanium dichloride; bis-triphenylphosphine-palladium(II) chloride in ethylene glycol dimethyl ether
T=60°C; 3 h;
参考文献
Tamaru, Yoshinao; Ochiai, Hirofumi; Yoshida, Zen-ichi
Tetrahedron Letters, 1984 , vol. 25, # 35 p. 3861 - 3864
反应条件
copper(l) iodide; sodium methylate; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in methanol; acetonitrile
T=20°C; 3 h;
参考文献
Kang; Ryu; Lee
Synthetic Communications, 2001 , vol. 31, # 7 p. 1059 - 1064
反应条件
copper(l) iodide; sodium hydrogencarbonate in ethylene glycol dimethyl ether; water
T=20°C; 0.5 h;
参考文献
Kang, Suk-Ku; Yoon, Seok-Keun; Kim, Young-Mook
Organic Letters, 2001 , vol. 3, # 17 p. 2697 - 2699
反应条件
C70H40Cl2F68N2O6Pd2; tetrabutylammomium bromide in water
T=100°C; Stille coupling; 0.0583333 h; Microwave irradiation;
参考文献
Susanto, Woen; Chu, Chi-Yuan; Ang, Wei Jie; Chou, Tzyy-Chao; Lo, Lee-Chiang; Lam, Yulin
Journal of Organic Chemistry, 2012 , vol. 77, # 6 p. 2729 - 2742
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=90°C; 2 h; Inert atmosphere;
参考文献
Rao, Maddali L. N.; Jadhav, Deepak N.; Dasgupta, Priyabrata
Organic Letters, 2010 , vol. 12, # 9 p. 2048 - 2051
反应条件
n-butyl-magnesium chloride; sodium methylate; sodium; Ca(OH)2 in tetrahydrofuran
T=0 - 20°C; Sonogashira Cross-Coupling; 0.0916667 h; Inert atmosphere;
参考文献
Jin, Guanyi; Zhang, Xuxue; Cao, Song
Organic Letters, 2013 , vol. 15, # 12 p. 3114 - 3117
反应条件
1: 4-ethynyl-1-methoxy-benzene With n-butyllithium in tetrahydrofuran; hexane
T=20°C; 1.5 h; Inert atmosphere;
2: Ph3B*Py in tetrahydrofuran; hexane
T=20°C; 1 h; Inert atmosphere;
3: With [VO(OEt)Cl2] in dichloromethane; acetonitrile
T=20°C; 2 h; Inert atmosphere;
参考文献
Amaya, Toru; Tsukamura, Yusuke; Hirao, Toshikazu
Advanced Synthesis and Catalysis, 2009 , vol. 351, # 7-8 p. 1025 - 1028
反应条件
potassium phosphate; palladium diacetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in dimethyl sulfoxide
T=65°C; Sonogashira coupling; 16 h; Inert atmosphere;
参考文献
Shirbin, Steven J.; Boughton, Berin A.; Zammit, Steven C.; Zanatta, Shannon D.; Marcuccio, Sebastian M.; Hutton, Craig A.; Williams, Spencer J.
Tetrahedron Letters, 2010 , vol. 51, # 22 p. 2971 - 2974
反应条件
trifuran-2-yl-phosphane; sodium carbonate; tris-(dibenzylideneacetone)dipalladium(0) in 1,4-dioxane
T=65°C; Arylation; Suzuki reaction; Dehydrobromination;
参考文献
Shen, Wang
Synlett, 2000 , # 5 p. 737 - 739
反应条件
1: tri-phenyl-antimony With [bis(acetoxy)iodo]benzene in dichloromethane
T=20°C; 7 h;
2: 2-(4-methoxyphenyl)-1-trimethylsilyl-ethyne With tris(dibenzylideneacetone)dipalladium(0) chloroform complex; copper(l) iodide in acetonitrile
T=50°C; 5 h; Further stages.;
参考文献
Kang, Suk-Ku; Ryu, Hyung-Chul; Hong, Young-Taek
Journal of the Chemical Society. Perkin Transactions 1, 2001 , # 7 p. 736 - 739
