Boc-L-天冬氨酸-4-环己酯合成路线 （共 14 条）
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran Ambient temperature;
参考文献
Namikoshi, Michio; Kundu, Bijoy; Rinehart, Kenneth L.
Journal of Organic Chemistry, 1991 , vol. 56, # 18 p. 5464 - 5466
反应条件
triethylamine in N,N-dimethyl-formamide 12 h; Ambient temperature;
参考文献
Toth; Penke
Synthesis, 1992 , # 4 p. 361 - 362
反应条件
piperidine in acetonitrile 12 h; Ambient temperatureor with 1,8-diazobicyclo<5.4.0>undec-7-ene in dioxane;
参考文献
Kalashnikov, V. V.; Samukov, V. V.
Chemistry of Natural Compounds, 1990 , vol. 26, # 2 p. 196 - 198
Khimiya Prirodnykh Soedinenii, 1990 , # 2 p. 241 - 245
反应条件
hydrogen; palladium on activated charcoal in ethyl acetate
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 8 p. 1901 - 1913
反应条件
1: DMAP; EDC-HCl / CH2Cl2 / 20 °C 2: H2 / Pd/C / ethyl acetate View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 8 p. 1901 - 1913
反应条件
1: DMAP; EDC-HCl / CH2Cl2 / 20 °C 2: H2 / Pd/C / ethyl acetate View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 8 p. 1901 - 1913
反应条件
1: ethyl acetate / 1 h / Ambient temperature 2: 95 percent / dicyclohexylcarbodiimide, 4-diethylaminopyridine / acetonitrile / 1) 0 deg C, 1 h, 2) 5 deg C, 12 h 3: 92 percent / piperidine / acetonitrile / 12 h / Ambient temperature; or with 1,8-diazobicyclo<5.4.0>undec-7-ene in dioxane View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 26, # 2 p. 196 - 198
Khimiya Prirodnykh Soedinenii, , # 2 p. 241 - 245
反应条件
1: 95 percent / dicyclohexylcarbodiimide, 4-diethylaminopyridine / acetonitrile / 1) 0 deg C, 1 h, 2) 5 deg C, 12 h 2: 92 percent / piperidine / acetonitrile / 12 h / Ambient temperature; or with 1,8-diazobicyclo<5.4.0>undec-7-ene in dioxane View Scheme
参考文献
Chemistry of Natural Compounds, , vol. 26, # 2 p. 196 - 198
Khimiya Prirodnykh Soedinenii, , # 2 p. 241 - 245
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Nishino, Norikazu; Xu, Ming; Mihara, Hisakazu; Fujimoto, Tsutomu; Ueno, Yukio; Kumagai, Hiromichi
Tetrahedron Letters, 1992 , vol. 33, # 11 p. 1479 - 1482
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Nishino, Norikazu; Xu, Ming; Mihara, Hisakazu; Fujimoto, Tsutomu; Ueno, Yukio; Kumagai, Hiromichi
Tetrahedron Letters, 1992 , vol. 33, # 11 p. 1479 - 1482
