3,4'-二甲基-1,1'-联苯合成路线 （共 62 条）
反应条件
Co(II)TMeOPP; potassium hydroxide; tert-butyl alcohol
T=200°C; 2 h; Inert atmosphereDarkness;
参考文献
To, Ching Tat; Chan, Tek Long; Li, Bao Zhu; Hui, Ying Ying; Kwok, Tsz Yiu; Lam, Suet Yu; Chan, Kin Shing
Tetrahedron Letters, 2011 , vol. 52, # 9 p. 1023 - 1026
反应条件
AlCl3, aluminium chloride in 1,4-dioxane
T=20°C; 4.5 h;
参考文献
Narender, Tadigoppula; Sarkar, Satinath; Rajendar, Kandikonda; Tiwari, Sriniwas
Organic Letters, 2011 , vol. 13, # 23 p. 6140 - 6143
反应条件
lithium in tetrahydrofuran
T=25°C; 2 h; sonication;
参考文献
Price, Gareth J.; Clifton, Andrew A.
Tetrahedron Letters, 1991 , vol. 32, # 48 p. 7133 - 7134
反应条件
tri-tert-butyl phosphine; tris(dibenzylideneacetone)dipalladium(0) chloroform complex in ethylene glycol dimethyl ether; hexane
T=20°C;
参考文献
Saeki, Tomoyuki; Matsunaga, Tadafumi; Son, Eun-Cheol; Tamao, Kohei
Advanced Synthesis and Catalysis, 2004 , vol. 346, # 13-15 p. 1689 - 1692
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in toluene
Suzuki-Miyaura reaction; 24 h; Heating;
参考文献
Cammidge, Andrew N.; Goddard, Victoria H. M.; Gopee, Hemant; Harrison, Nicola L.; Hughes, David L.; Schubert, Christopher J.; Sutton, Benjamin M.; Watts, Gary L.; Whitehead, Andrew J.
Organic Letters, 2006 , vol. 8, # 18 p. 4071 - 4074
反应条件
caesium carbonate; 9-BnFluPiPr2*HBF4; Na2[PdCl4] in 1,4-dioxane
T=45 - 100°C; Suzuki Coupling; 3.5 - 14 h; Product distribution / selectivity;
参考文献
Evonik Degussa GmbH
Patent: EP1894938 A1, 2008 ;
Location in patent: Page/Page column 48; 51; 52 ;
反应条件
tetrabutylammomium bromide; palladium diacetate in water
T=20°C; Suzuki-Miyaura coupling; 8 h;
参考文献
Basu, Basudeb; Biswas, Kinkar; Kundu, Sekhar; Ghosh, Sujit
Green Chemistry, 2010 , vol. 12, # 10 p. 1734 - 1738
反应条件
bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide in neat (no solvent)
T=110°C; Suzuki-Miyaura Coupling; 24 h; Schlenk techniqueInert atmosphere;
参考文献
Asachenko, Andrey F.; Sorochkina, Kristina R.; Dzhevakov, Pavel B.; Topchiy, Maxim A.; Nechaev, Mikhail S.
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 18 p. 3553 - 3557
反应条件
lithium in tetrahydrofuran
T=25°C; 2 h; sonication;
参考文献
Price, Gareth J.; Clifton, Andrew A.
Tetrahedron Letters, 1991 , vol. 32, # 48 p. 7133 - 7134
反应条件
1: in tetrahydrofuran; toluene
T=20°C; Inert atmosphere;
2: With 2,3-dicyano-5,6-dichloro-p-benzoquinone in tetrahydrofuran; toluene
T=20 - 100°C; Inert atmosphere;
参考文献
Zhou, Feng; Simon, Marc-Oliver; Li, Chao-Jun
Chemistry - A European Journal, 2013 , vol. 19, # 22 p. 7151 - 7155
