3,4'-二甲基-1,1'-联苯合成路线 （共 62 条）
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h / -20 °C
1.2: 1.33 h / -20 - 20 °C
2.1: AlCl3, aluminium chloride / 1,4-dioxane / 4.5 h / 20 °C
View Scheme
参考文献
Narender, Tadigoppula; Sarkar, Satinath; Rajendar, Kandikonda; Tiwari, Sriniwas
Organic Letters, 2011 , vol. 13, # 23 p. 6140 - 6143
反应条件
C15H14ClN4Pd(1+)*F6P(1-); caesium carbonate in water
T=100°C; Suzuki-Miyaura coupling reaction; 2 h;
参考文献
Chen, Chao; Qiu, Huayu; Chen, Wanzhi
Journal of Organometallic Chemistry, 2012 , vol. 696, # 26 p. 4166 - 4172
反应条件
dimethoxy sulfoxide
2 h; Heating; Yield given;
参考文献
Hara, Yoshinori; Matsuda, Minoru
Phosphorus and Sulfur and the Related Elements, 1983 , vol. 16, p. 211 - 222
反应条件
Tl(OCOCF3)3; palladium diacetate
T=70°C; 40 h; Yield given. Further byproducts given. Yields of byproduct given;
参考文献
Yatsimirsky, Anatoly K.; Deiko, Sergei A.; Ryabov, Alexander D.
Tetrahedron, 1983 , vol. 39, # 14 p. 2381 - 2392
反应条件
Wilkinson's catalyst
T=285°C;
参考文献
Blum,J. et al.
Journal of Organic Chemistry, 1970 , vol. 35, p. 3233 - 3237
反应条件
1: zinc / tetrahydrofuran; N,N-dimethyl-formamide / 20 °C
2: sulfuric acid / dichloromethane / 0.2 h / 20 °C
View Scheme
参考文献
He, Yan; Zhang, Xin-Ying; Cui, Liang-Yan; Fan, Xue-Sen
Chemistry - An Asian Journal, 2013 , vol. 8, # 4 p. 717 - 722
反应条件
sulfur in quinoline
Heating;
参考文献
Takahara, Shigeru; Urano, Tishiyuki; Kitamura, Akihide; Sakuragi, Hirochika; Kikuchi, Osamu; et al
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 2 p. 688 - 697
反应条件
1: diethyl ether
2: 2.) DDQ / 1.) chlorobenzene, heating; 2.) chlorobenzene, heating
View Scheme
参考文献
Bapat, Jayant B.; Brown, Roger F.C.; Bulmer, Glenn H.; Childs, Trevor; Coulston, Karen J.; Eastwood, Frank W.; Taylor, Dennis K.
Australian Journal of Chemistry, 1997 , vol. 50, # 12 p. 1159 - 1182
反应条件
1: diethyl ether
2: 2.) DDQ / 1.) chlorobenzene, heating; 2.) chlorobenzene, heating
View Scheme
参考文献
Bapat, Jayant B.; Brown, Roger F.C.; Bulmer, Glenn H.; Childs, Trevor; Coulston, Karen J.; Eastwood, Frank W.; Taylor, Dennis K.
Australian Journal of Chemistry, 1997 , vol. 50, # 12 p. 1159 - 1182
反应条件
1: Mg
2: sulfur / quinoline / Heating
View Scheme
参考文献
Takahara, Shigeru; Urano, Tishiyuki; Kitamura, Akihide; Sakuragi, Hirochika; Kikuchi, Osamu; et al
Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 2 p. 688 - 697
