6-[O-(2-溴乙基)磷酰)羟基己酸叔丁酯合成路线 （共 7 条）
反应条件
1: 93 percent / H2SO4 / CH2Cl2 / Ambient temperature 2: 1) sodium formate, 2) KOH / 1) DMF, a) 110 deg C, 4h, b) RT, 2 days, 2) H2O, 30-40 deg C, 4h 3: 1) triethylamine, 2) pyridine, H2O / 1) RT, 1h, 2) RT View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 15 p. 3081 - 3084
反应条件
1: 1) sodium formate, 2) KOH / 1) DMF, a) 110 deg C, 4h, b) RT, 2 days, 2) H2O, 30-40 deg C, 4h 2: 1) triethylamine, 2) pyridine, H2O / 1) RT, 1h, 2) RT View Scheme
参考文献
Journal of Organic Chemistry, , vol. 45, # 15 p. 3081 - 3084
反应条件
pyridine; water; triethylamine 1) RT, 1h, 2) RT; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 45, # 15 p. 3081 - 3084
反应条件
1: 40 percent / CHCl3 / 8 h / Heating 2: 92 percent / Dowex-50(H+) resin / H2O / 0.5 h / steam bath View Scheme
参考文献
Spande, Thomas F.
Journal of Organic Chemistry, 1980 , vol. 45, # 15 p. 3081 - 3084
反应条件
in chloroform 8 h; Heating;
参考文献
Journal of Organic Chemistry, , vol. 45, # 15 p. 3081 - 3084
反应条件
1: 34 percent / CHCl3 / 8 h / Heating 2: DCC / dimethylformamide View Scheme
参考文献
Spande, Thomas F.
Journal of Organic Chemistry, 1980 , vol. 45, # 15 p. 3081 - 3084
反应条件
in chloroform
8 h; Heating;
参考文献
Spande, Thomas F.
Journal of Organic Chemistry, 1980 , vol. 45, # 15 p. 3081 - 3084
