1: With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran; hexanes T=-78 - 0°C; 0.916667 h; 2: With iodine in tetrahydrofuran; hexanes T=0 - 25°C; 1.25 h; 3: in methanol T=25°C; 2 h;

hydrogenchloride 15 h; Heating;

1: 1.) n-BuLi, 2.) I2 / 1.) THF, -78 deg C - 0.5 h, room temperature - 1 h, 2.) THF, -78 deg C - 1 h, room temperature - 2 h 2: aq. HCl / 15 h / Heating View Scheme

sulfuric acid; sodium nitrite Anschliessend Behandeln mit wss. KI;