2’,3’,5’-三乙酰腺苷合成路线 （共 40 条）
反应条件
immobilized Pseudomonas fluorescens lipase in acetonitrile T=20°C; pH=7.0; 24 h; aq. phosphate bufferEnzymatic reaction; regioselective reaction;
参考文献
Bavaro, Teodora; Rocchietti, Silvia; Ubiali; Filice, Marco; Terreni, Marco; Pregnolato, Massimo
European Journal of Organic Chemistry, 2009 , # 12 p. 1967 - 1975
反应条件
1: 47 percent / tert-butyl nitrite; SbCl3 / CH2Cl2 / Heating 2: 61 percent / NH3 / methanol / -5 - 0 °C View Scheme
参考文献
Francom, Paula; Janeba, Zlatko; Shibuya, Susumu; Robins, Morris J.
Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6788 - 6796
反应条件
1: 69 percent / n-pentyl nitrite / tetrahydrofuran / 72 h / 50 °C 2: 77 percent / NaOMe View Scheme
参考文献
Nair; Chamberlain
Synthesis, 1984 , vol. NO. 5, p. 401 - 403
反应条件
n-Pentyl nitrite in tetrahydrofuran T=50°C; 72 h;
参考文献
Nair; Chamberlain
Synthesis, 1984 , vol. NO. 5, p. 401 - 403
反应条件
tert.-butylnitrite in tetrahydrofuran T=60°C; 0.333333 h;
参考文献
Francom, Paula; Janeba, Zlatko; Shibuya, Susumu; Robins, Morris J.
Journal of Organic Chemistry, 2002 , vol. 67, # 19 p. 6788 - 6796
反应条件
1: DMAP / 130 °C 2: 55 percent / tetrabutylammonium nitrate (TBAN); trifluoroacetic anhydride (TFAA) / CH2Cl2 / 0 °C 3: 10 percent / KCN / methanol 4: 80 percent / H2 / Raney Ni View Scheme
参考文献
Deghati, Paymaneh Y. F.; Wanner, Martin J.; Koomen, Gerrit-Jan
Tetrahedron Letters, 2000 , vol. 41, # 8 p. 1291 - 1295
反应条件
1: 88 percent / pyridine / 20 h / 100 °C 2: 99.8 percent / H2O / 0.67 h / Ambient temperature View Scheme
参考文献
Miles, Robert W.; Samano, Vicente; Robins, Morris J.
Journal of the American Chemical Society, 1995 , vol. 117, # 22 p. 5951 - 5957
反应条件
hydroxylammonium acetate in pyridine 24 h; Ambient temperature;
参考文献
Ishido, Yoshiharu; Sakairi, Nobuo; Okazaki, Kei; Nakazaki, Nobuo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 563 - 573
反应条件
hydroxylammonium acetate in pyridine 48 h; Ambient temperature;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 563 - 573
反应条件
1: DMAP / 130 °C
2: 55 percent / tetrabutylammonium nitrate (TBAN); trifluoroacetic anhydride (TFAA) / CH2Cl2 / 0 °C
3: 47 percent / KCN / methanol
View Scheme
参考文献
Deghati, Paymaneh Y. F.; Wanner, Martin J.; Koomen, Gerrit-Jan
Tetrahedron Letters, 2000 , vol. 41, # 8 p. 1291 - 1295
